NL-OMON47993已完成不适用
High-fat challenge induced trained innate immunity - The SHAKE study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 16
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99(—)
入选标准
- •Age between 18 and 40 years
- •LDL cholesterol < 3.5 mmol/l, fasting triglycerides < 2 mmol/l
- •No previous cardiovascular events
排除标准
- •Smoking within the year before study entry
- •Diagnosed with any long-term medical condition that can interfere with the study (i.e. renal failure, galbladder disease, cardiovascular disease, diabetes, rheumatoid arthritis etc.)
- •Medication (with the exception of oral contraceptives) or supplement use (i.e. omega3)
- •BMI < 18 or > 27 kg/m2
- •Previous vaccination within 3 months prior to study entry
- •Current infection or clinically significant infections within 1 month before study entry (defined as fever > 38.5°C)
- •Allergic to cow milk/dairy products
- •Pregnancy/lactation
- •Abuse of alcohol or drugs
- •Vegetarian diet
研究者
相似试验
尚未招募
不适用
The effect of a high-fat meal on the immune systematherosclerosisinnate immune memoryhigh-fat challengeslagaderverkalkinggeheugen van het aangeboren afweersysteemvetrijke maaltijdNL-OMON24430Radboud University Medical Center15
已完成
不适用
High-fat Challenge Induced Trained Innate Immunity (SHAKE Study)Cardiovascular DiseasesNCT05682456Radboud University Medical Center16
进行中(未招募)
1 期
Application of a TBE-Vaccine in obese personsStudies have shown that obesity has a direct effect on the immune system and leads to immunosuppression, which leads to a susceptibility to infection. The aim of this study is to clarify if a modification of vaccination schedules or a change of booster intervals is necessary for obese people. Furthermore this study will increase our understanding of the influence of obesity on different components of the immune system, as well as on the quality and quantity of the immune responses.EUCTR2014-000570-19-ATInstitute of Specific Prophylaxis and Tropical Medicine148
进行中(未招募)
不适用
Chronic inflammatory activation in fat tissue: an atherogenic factor in severe coronary artery disease.severe cardiovascular artery diseaseEUCTR2007-001888-29-DEniversity of Leipzig
已完成
不适用
Exercise, Prostate Cancer and Circulating Tumour CellsObesityProstate CancerNCT02453139University of Dublin, Trinity College67
