跳至主要内容
临床试验/EUCTR2004-001953-27-GB
EUCTR2004-001953-27-GB进行中(未招募)不适用

The Pharmacokinetics of Systemic Corticosteriods in Refractory Asthma

niversity Hospitals of Leicester NHS Trust0 个研究点目标入组 20 人开始时间: 2005年2月15日最近更新:
适应症
相关药物

试验速览

阶段
不适用
状态
进行中(未招募)
发起方
入组人数
20

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional clinical trial of medicinal product

入排标准

性别
All

入选标准

  • Asthma cases:
  • 1. Patients with refractory asthma (according to the American Thoracic Society Criteria for refractory asthma. Ref. American Journal of Respiratory and Critical Care Medicine 162(6):2341-2351)
  • 1.Healthy volunteers with no respiratory symptoms
  • Are the trial subjects under 18? no
  • Number of subjects for this age range:
  • F.1.2 Adults (18-64 years) yes
  • F.1.2.1 Number of subjects for this age range
  • F.1.3 Elderly (>=65 years) yes
  • F.1.3.1 Number of subjects for this age range

排除标准

  • 1. Current smokers or ex-smokers with more than 10-pack year smoking history
  • 2. Significant other co-morbidity, including hepatic, renal or endocrine dysfunction
  • 3. Pregnant or breast feeding women
  • 4. Concurrent oral medication likely to interfere with prednisolone pharmacokinetics, e.g. anti-convulsants
  • 5. Concurrent oral prednisolone at a dose of more than 10mg per day

研究者

发起方
niversity Hospitals of Leicester NHS Trust

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