Analgesic Efficacy of Combined Lumbar Erector Spinae Plane Block and Pericapsular Nerve Group Block in Patients Undergoing Hip Surgeries
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 24
- 试验地点
- 1
- 主要终点
- Postoperative pain intensity
研究概览
简要总结
The investigators are going to evaluate the postoperative analgesic efficacy of combined LESPB and PENG block after hip surgeries.
详细描述
Hip surgeries are very common surgeries and has high postoperative pain potential. There are different ways to execute postoperative analgesia and each of them has advantages and disadvantages. As the patients submitted to this procedure are usually older and with multiple comorbidities, analgesia options with better profile of adverse effects should be preferred. Peripheral nerve block with long-acting local anesthetics is very suitable in this situation, in comparison with systemic or neuraxial opioids.
Pain control after total hip arthroplasty (THA) can be challenging because of complex innervation of the hip joint from both the lumbar and sacral nerve plexus. pain was the cause of 12% of unplanned hospital patient admissions, 60% of these patients were admitted for orthopedic concerns. The consequences of severe postoperative pain are prolonged hospital stay, increase hospital readmission, precipitation in the use of opioids with subsequent increase in postoperative nausea and vomiting, and overall low patient satisfaction. Furthermore, postoperative pain can seriously impact the physical and mental health of the patient and lead to secondary complications such as nausea, vomiting, slowed bowel movements, muscle spasms, thrombosis, cardiopulmonary complications and delayed recovery of organ functions.
The hip joint is innervated by the articular branches of multiple nerves that emerge from the lumbosacral plexus (L2-S1). The nerve supply to a specific region of the joint typically corresponds to the innervation of the muscle that crosses it :-
- The femoral nerve innervates the anterior aspect
- The obturator nerve supplies the inferior aspect
- The superior gluteal nerve supplies the superior aspect
- The nerve to the quadratus femoris innervates the posterior aspect.
Hip joint capsular innervation was found to consistently involve the femoral and obturator nerves, which supply the anterior capsule, and the nerve to the quadratus femoris, which supplies the posterior capsule.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 70 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients aged 18-70 years old
- •American Society of Anesthesiologists (ASA) class I to III
- •Scheduled for hip surgery.
排除标准
- •Refusal to participate
- •Allergy to any of the study drugs
- •Bleeding disorder
- •Localized infection
- •Neurological disease
- •Renal impairment
- •Psychological disorders
- •Opioid dependent
- •Intellectual disability (patients unable to express pain with visual analogue)
- •Morbid obesity.
研究组 & 干预措施
Group A: L-ESPB and PENG
receiving after end of hip surgery (PENG) block first and (LESPB) at lumber 4 vertebrae level
干预措施: Ultrasound guided L-ESPB and PENG block using Bupivacaine (Procedure)
Group B: conventional analgesia
receiving postoperative conventional analgesia in form of acetaminophen 15 mg/kg/6hrs
干预措施: Postoperative conventional analgesia in form of Acetaminophen (Drug)
结局指标
主要结局
Postoperative pain intensity
时间窗: at 24 hour after the block
Postoperative pain intensity using Visual Analogue Scale (VAS) (which is over 10 centimeter scale) (where 0 indicates no pain at all , 10 indicates severe pain)
次要结局
- Vital signs(assessed at preoperative, postoperative (0,3,6,12,24 hours), Value is averaged of total measurements)
- Time to first analgesic administration(24 hours postoperative)
- Patient satisfaction(24 hours after the block)
- Total Analgesic Requirements(24 hours postoperative)
- Block failure (patients still feeling pain immediately after 1 hour from block)(1 hour after the block)
- Adverse events(24 hours after the block)
研究者
Ibrahim Walash
Assistant Lecturer of anesthesia, intensive care and pain management
Menoufia University
