New Approach to Increasing Gingival Thickness in Individuals With Fine Gingival Phenotype:Injectable Platelet Rich Fibrin (I-PRF)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 29
- 试验地点
- 1
- 主要终点
- Gingival thickness (mm)
研究概览
简要总结
The main objective of this study is to investigate whether the for individuals with thin gingival thickness who are susceptible to gingival recession, the investigators will use i-PRF with microneedle to increase gingival thickness without the need for surgical procedures
详细描述
Due to the thin gingival phenotype, gingival recession is a problem. The investigators aimed to increase the gingival thickness using i-PRF with microneedle without considering surgical procedures, considering the positive effects of platelet concentrations on revascularization and wound healing in individuals with bone defect, fenestration and gingival thickness which are prone to gingival recession .
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Never smokers
- •Had no history of systemic disease
- •Aged ≥18 years old
排除标准
- •Patients with a history of diabetes mellitus or systemic disease
- •Patients who were under any medication that was known to influence periodontal tissues
- •Patients with hormonal changes such as pregnancy or lactation
- •Toothless individuals
- •Patients who were clotting disorders
研究组 & 干预措施
I-PRF
Venous blood will be taken from the patient every session and I-PRF will be created in the centrifuge.I-PRF injected on one side of bilateral thin gingival thickness.Apply once a week and one month after the end of the injections, the patient will be called to the control.
干预措施: I-PRF (Other)
I-PRF and Microneedling
Venous blood will be taken from the patient every session and I-PRF will be created in the centrifuge.Microneedle application plus I-PRF injected on the other side in patients with bilateral region with thin gingival phenotype.Apply once a week and one month after the end of the injections, the patient will be called to the control.
干预措施: I-PRF (Other)
结局指标
主要结局
Gingival thickness (mm)
时间窗: 2 months
Change in clinical measures of gingival thickness
次要结局
- Gingival Index (GI)(2 months)
- Plaque Index (PI)(2 months)
- Bleeding on probing (BOP)(2 months)
- Clinical attachment level (CAL)(2 months)
- Probing pocket depth (PD)(2 months)