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临床试验/NCT06794177
NCT06794177已完成不适用

Investigation of the Effects of Dual Task Training With Different Task Priorities on Physical Performance and Cognitive Status in Patients With Parkinson's Disease

Hacettepe University2 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2024年2月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
30
试验地点
2
主要终点
Functional Reach Test

研究概览

简要总结

This study was planned to investigate and compare the effects of variable and fixed priority dual task training on balance, walking skills, mobility and cognition in patients with Parkinson's disease.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
40 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Having agreed to participate in the research after being given detailed information about the research.
  • •Having been diagnosed with Parkinson's disease by a specialist neurologist according to the UK Brain Bank criteria
  • •Being in stage 1-3 according to Hoehn & Yahr
  • •Being 40 years of age or older

排除标准

  • •Having a neurological condition other than Parkinson's disease
  • •Cognitive impairment
  • •Have undergone deep brain stimulation surgery
  • •Having a visual, auditory or perceptual problem
  • •Having any orthopedic, rheumatological or other disease that may affect walking and balance.

研究组 & 干预措施

Contol Group

Active Comparator

Single task training

干预措施: Single task training (Other)

Variable priority dual task training group

Experimental

Variable priority dual task training

干预措施: Variable priority dual task training (Other)

Fixed priority dual task training group

Experimental

Fixed priority dual task training

干预措施: Fixed priority dual task training (Other)

结局指标

主要结局

Functional Reach Test

时间窗: Baseline, 6 weeks

The test is designed to assess dynamic balance by measuring the maximum distance that a person can reach forward beyond arm's length without taking a step.

Single Leg Stance Test

时间窗: Baseline, 6 weeks

It is a test method used to evaluate static balance. One foot is lifted without touching the supporting leg and the person is expected to maintain their balance for 30 seconds.

Four Square Step Test

时间窗: Baseline, 6 weeks

It is a test method used to evaluate dynamic balance. Two canes are placed on a flat surface to create 4 squares. All squares are numbered. The subject starts in one square and steps in one direction into each of the four squares and then reverses direction back to the start. The time (in seconds) taken to complete the sequence is measured.

10 Meter Walk Test

时间窗: Baseline, 6 weeks

Used to assess walking speed. Participants are asked to walk a distance of 10 meters and the time taken is recorded.

3-Meter Backward Walk Test

时间窗: Baseline, 6 weeks

The 3-meter distance is measured and marked. Participants are asked to walk backwards as quickly as possible with the "walk" command and to stop when they reach 3 meters. The elapsed time is recorded in seconds.

Timed Up and Go Test

时间窗: Baseline, 6 weeks

It is used to assess functional mobility level. The participant is asked to stand up from the chair, walk 3 m, turn around, walk back to the chair and sit down. The test starts with the "walk" command and the completion time is recorded in seconds.

Dual Task Questionnaire

时间窗: Baseline, 6 weeks

It is used to obtain information about the difficulties experienced in daily tasks related to dual task. It consists of 10 questions, each question is scored between 0 and 4.

Hoehn and Yahr Scale

时间窗: Baseline, 6 weeks

A staging system that quickly provides information in determining the degree and symptom severity of the disease

Unified Parkinson's Disease Rating Scale

时间窗: Baseline, 6 weeks

Evaluates cognitive skills, mood, activities of daily living, motor skills, motor fluctuations, dyskinesias, and autonomic dysfunction in four parts

Berg Balance Scale

时间窗: Baseline, 6 weeks

It includes 14 functional activities to assess static and proactive balance. The total score ranges from 0 to 56, with higher scores indicating better balance.

Figure-of-Eight Walk Test

时间窗: Baseline, 6 weeks

The participant stands still at the midpoint of two cones placed 1.52 m apart and begins walking around the cones in a figure eight at his/her usual pace. The total time and number of steps taken to complete the test are recorded.

Unified Parkinson's Disease Rating Scale, Part 2

时间窗: Baseline, 6 weeks

UPDRS Part 2 generally is considered a psychometrically reliable tool for measuring activities of daily living outcomes in people with Parkinson's disease.

Trail Making Test

时间窗: Baseline, 6 weeks

It is used to evaluate individuals' visual scanning speed, executive functions, visual-motor perception, motor function, planning, organization, abstract thinking and response limitation. The test consists of 2 parts: A and B. In part A, the individual is asked to combine numbers from 1 to 25 and the completion time is recorded. In part B, the individual completes the sequence by corresponding to a number and a letter, and the completion time is recorded.

Stroop Test

时间窗: Baseline, 6 weeks

It is a test that evaluates executive functions and the suppression of inappropriate automatic responses and provides information about frontal functions.

Symbol Digit Modalities Test

时间窗: Baseline, 6 weeks

It is a test that measures working memory and information processing speed. In the upper right corner of the A4 paper used in the test, there is a grid of shapes, each representing a number. In the other parts of the paper, there are randomly arranged shapes in blocks. During the test, patients are asked to match these shapes with the numbers in the grid.

Word List Generation

时间窗: Baseline, 6 weeks

It is a test used to evaluate complex attention functions and vocabulary. It consists of animal and KAS sections. First, the patient is asked to name every animal that comes to mind in one minute, as quickly as possible. In the KAS section, the patient is asked to name every word that comes to mind, except for proper nouns and city names, with the letters K-A-S in order. The time for each letter is again one minute.

Tampa Scale for Kinesiophobia

时间窗: Baseline, 6 weeks

It is a 17-question scale developed to measure fear of movement/re-injury. The scale includes parameters of injury/re-injury and fear-avoidance in work-related activities. Each item is scored between 1-4.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Elvan ÖZCAN GÜLŞEN

Lecturer

Hacettepe University

研究点 (2)

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