Accuracy of FNAC in Diagnosis of Thyroid Nodules
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 100
- 主要终点
- Incidence of true positive results of FNAC after thyroidectomy
研究概览
简要总结
Detection of degree of accuracy of FNAC in diagnosis of thyroid nodules
详细描述
Accuracy in diagnosis in any case is required, and this is beneficial to the patient and the physician, and with the development that currently exists and the trend to use less invasive techniques, accuracy of FNAC should be studied well.1.Thyroid nodules are common and the principal method of diagnosis is fine-needle aspiration cytology (FNAC).2. Can investigators depend on FNAC alone in diagnosis of thyroid nodule in the future?!3. In this study, investigators will compare the results of (FNAC) versus (Biopsy) in diagnosis of thyroid nodule in AUH , to detect the degree of accuracy of FNAC.4. FNAC is a simple, safe, cost-effective and accurate diagnostic tool for the initial screening of patients with thyroid nodules.5. Background Routine application of fine needle aspiration cytology (FNAC) has decreased unnecessary referral of thyroid nodules for surgical treatment and has also increased the cancer rates found in surgery materials. Success of thyroid FNAC depends on skilled aspiration, skilled cytological interpretation and rational analysis of cytological and clinical data. The aim of this study was to determine the diagnostic accuracy rates of thyroid FNAC results obtained in our hospital.6. The FNAC is a sensitive, specific, and accurate initial diagnostic test for the preoperative evaluation of patients with thyroid swellings in our setting as well. The correlation of cytological and histopathological diagnoses is an important quality assurance method, as it allows cytopathologists to calculate their false-positive and false negative results.7
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 10 Years 至 80 Years(Child, Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •thyroid disease
- •multinodular
- •single nodule
- •TIRAD 3 or more by US
- •thyroid disease underwent FNAC then surgery
- •all age groups
- •patient fit for surgery
排除标准
- •patients with comorbidities.
- •patients unfit for surgery
- •patients who refused surgery.
- •Patient with no diagnostic FNAC.
结局指标
主要结局
Incidence of true positive results of FNAC after thyroidectomy
时间窗: 12 days
Accuracy of FNAC in thyroid nodules compared to surgical specimen histopathological examination
Percentage of malignant thyroid nodules not observed by FNAC
时间窗: 12 days
Percentage of malignant thyroid nodules that FNAC fails to detect
Incidence of false negative results by FNAC
时间窗: 12 days
False negative that diagnosed by FNAC not malignant but proved malignancy after surgical excision
Percentage of total number of true results of FNAC to the total number of cases
时间窗: 12 days
Accuracy of FNAC
次要结局
未报告次要终点
研究者
Mostafa Abed Abdulmoneim Mohammed
Principal Investigator
Assiut University
