Implementing and Testing a Culturally-Tailored Stroke Risk Factor Reduction Intervention in Community Senior Centers
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 240
- 试验地点
- 8
- 主要终点
- Change from Baseline in Mean steps/day at 3 months
研究概览
简要总结
Stroke is a cruel disease that disproportionately kills and disables African-Americans, Latinos, Chinese-Americans and Korean-Americans; seniors with high blood pressure are at particularly high risk. There is a higher incidence of hemorrhagic stroke in African Americans, Latinos, and Chinese Americans relative to non-Latino whites. Asian-Americans have up to 1.4 higher relative risk of stroke death compared to U.S. non-Latino whites. A critical need therefore exists for a sustainable and scalable mechanism to disseminate culturally-tailored stroke knowledge/prevention education in community-based settings where large numbers of these high-risk ethnic minority older adult groups are regularly served, such as in federally funded Multipurpose Senior Centers (MPCs) that exist across the nation (16 of which are in Los Angeles alone).
The overall objective of the proposed study is to develop and test the implementation of a training program for case managers at senior centers to implement a stoke knowledge/prevention education program among four high-risk ethnic minority older adult groups--Korean-American, Chinese-American, African-American, Latinos. We propose to develop a culturally-tailored case manager training curriculum, implement the training at 4 community-based sites, and evaluate the training model using a randomized wait-list controlled trial (n=244) testing the hypothesis that training case managers will decrease older adult participants' stroke risk in a sustainable fashion through increasing their preventative behavior (i.e. increasing their physical activity--mean steps/day--at 1 and 3 months).
Findings will inform similar community-academic partnership efforts around stroke and other disease-specific prevention research/interventions; they will also determine next steps in terms of whether this case manager-centric model can be scaled up and deployed in other community-based settings.
详细描述
As many as 30% of ischemic strokes in the U.S. population can be attributed to physical inactivity. With the goal of eliminating racial/ethnic stroke disparities, this interdisciplinary team proposes to develop, implement, and test a culturally-tailored behavioral intervention to reduce stroke risk (primary prevention) by increasing physical activity (walking) for 4 different racial/ethnic groups (Korean-Americans, Chinese-Americans, African-Americans and Latinos) in Los Angeles community senior centers. The intervention combines stroke and stroke risk factor knowledge (using materials developed by the American Heart Association and American Stroke Association) with theoretically-grounded behavioral change techniques and focuses on reducing stroke risk by increasing physical activity (walking). The study team will conduct focus groups (n=144) to identify culture-specific beliefs about stroke and stroke risk factors, to assess the feasibility and acceptability of the intervention, and will work with Community Action Panels to culturally-tailor the intervention. The intervention will consist of 4 weeks of twice-weekly 1-hour group sessions implemented at 4 community senior centers by trained case managers who are part of the regular senior center staff and supported by congressionally-mandated Older Americans Act Title III funding. The project team will test the effectiveness of the intervention in a randomized wait-list controlled trial (n=240) testing the hypothesis that the intervention will increase mean steps/day (measured by pedometer) at 1 and 3 months, and that the increase will be mediated by changes in stroke/stroke risk knowledge and self-efficacy. Blood pressure will be examined as a secondary outcome. In collaboration with the SPIRP Biomarker Collection & Analysis Core, the team will collect biological specimens (finger pricks) to explore the relationship between the intervention and biological markers of health; they will also explore the relationship between the intervention and healthcare seeking or taking medications to control stroke risk factors. The team will evaluate the barriers and facilitators of successfully integrating the intervention into the senior centers in order to inform large-scale implementation of the culturally-tailored stroke risk factor reduction/walking intervention.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age 60 years and older
- •reported history of high blood pressure
排除标准
- •younger than 60 years of age
- •not self-identifying as the racial-ethnic group for the intervention planned at that site
- •inability to communicate verbally in the appropriate language in a group setting (either due to lack of language skills, hearing impairment, or other disability)
- •inability to sit in a chair and participate in a 1-hour discussion session
- •inability to walk (the use of assistive devices such as canes and walkers is not an exclusion criterion)
- •not available to attend the baseline data collection session and subsequent weekly intervention sessions
- •plans to move away from the region during the next 6 months
- •lacking cognitive capacity to provide informed consent to participate
结局指标
主要结局
Change from Baseline in Mean steps/day at 3 months
时间窗: 3 months
Measured via pedometer.
Change from Baseline in Mean Steps/day at 1 month
时间窗: 1 month
Measured via pedometer.
次要结局
- Disability(baseline, 1 month, and 3 months)
- Medical comorbidities(Baseline)
- Stroke and stroke risk factor knowledge(baseline, 1 month, and 3 months)
- BMI (kg/m^2)(baseline, 1 month, and 3 months)
- Blood pressure(baseline, 1 month, and 3 months)
- Self Efficacy(baseline, 1 month, and 3 months)
- LDL cholesterol(baseline and 3 months)
- Glycosylated hemoglobin(baseline and 3 months)
- c-reactive protein(baseline and 3 months)
- Healthcare seeking(baseline and at 3 months)
- Socioeconomic status(baseline)
- Social support/network(Baseline, 1 month, 3 months)
- Health-related QOL(baseline, 1 month, and 3 months)
- Medications to control stroke risk factors(baseline and at 3 months)
- Acculturation(Baseline)
- Depressive symptoms(baseline, 1 month, and 3 months)
- Neighborhood Walkability(baseline)
研究者
Catherine A. Sarkisian
Director, L.A. CAPRA Center
University of California, Los Angeles