Sarcopenia in Acute Care Patients: Protocol for the European Collaboration of Geriatric Surveys: Sarcopenia 9+ European Academy for Medicine of Ageing (EAMA) Project
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 366
- 试验地点
- 1
- 主要终点
- Incidence of sarcopenia as defined by the European consensus on definition and diagnosis (EWGSOP2)
研究概览
简要总结
This collaborative study in 9 geriatrics units across Europe aims to apply emerging research to clinical practice, following the "Action-Research Philosophy" (11). The overall goal is to improve care in patients with - and help prevent - sarcopenia. Understanding the frequency of and risk factors for developing sarcopenia in an acute hospital setting, may help shed light on potential interventions and thus inform the development of future therapeutic strategies. It involves crucial implications for research, clinical practice, and policy towards optimal aging.
详细描述
Background: Sarcopenia is a nutrition-related disease leading to physical impairment and adverse clinical outcomes. Data regarding its characteristics in hospitalized patients are limited.
Aim: This study will assess in older patients admitted to acute medical wards, the prevalence, incidence, and risk factors for development of sarcopenia, or alteration in its severity, and evaluate associated clinical adverse outcomes.
Methods: This collaboratively-designed, longitudinal prospective observational study will be carried out in patients aged >70 admitted to acute geriatric units in 9 European centers. The new sarcopenia diagnostic criteria of the European Working Group on Sarcopenia 2 (EWGSOP2) will be tested at admission and discharge, using isometric handgrip dynamometry, gait speed, and, pragmatically, calf circumference. There will be 3- and 12-month telephone follow-up (including the SARC-F questionnaire).
Discussion: Our study will be the first collaboration to assess the prevalence and incidence of sarcopenia (EWGSOP2) and its risk factors in hospitalized patients across Europe.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 70 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged >70 admitted to acute hospital medical units
排除标准
- •Length of hospital stay anticipated to be <24 hours
- •Hip/lower limb fractures
- •Major amputations of the lower leg
- •Terminally ill patients admitted for palliative care
结局指标
主要结局
Incidence of sarcopenia as defined by the European consensus on definition and diagnosis (EWGSOP2)
时间窗: One year (March 2019-March 2020)
Incidence of sarcopenia in acute hospitalized older patients.
Prevalence of sarcopenia as defined by the European consensus on definition and diagnosis (EWGSOP2)
时间窗: One year (March 2019-March 2020)
Prevalence sarcopenia in acute hospitalized older patients.
次要结局
未报告次要终点