Neutralizing Antibody Level After COVID-19 Vaccination in Hospital Works.
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 51
- 试验地点
- 1
- 主要终点
- titer of neutralizing antibody after COVID-19 vaccination
研究概览
简要总结
- serial of neutralizing antibody at 2, 4, 6, 9, 12 month after COVID-19 vaccination
- investigate the factors on antibody titer.
详细描述
- serial of neutralizing antibody at 2, 4, 6, 9, 12 month after COVID-19 vaccination 1) semi-quantitative measurement of neutralizing antibody at 2, 4, 6, 9, 12 month after COVID-19 vaccination 2) investigate the duration maintaining acceptable range (over 30% inhibition)
- investigate the factors on antibody titer at 2 month after vaccination 1) potential factors: age, sex, body weight, height, use of medication, use of antipyretics (NSAID or tyrenol), side effect of COVID-19 vaccination 2) correlation between antibody titer and potential factors
- Compare 4 diagnostic ELISA kit at 2 month after vaccination 1) measure neutralizung antibody using ELISA kits from 4 different companies 2) investigate correlation coefficient of antibody titer between companies
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •healthcare works after completion of COVID-19 vaccination
- •20-60 years
- •sign the agreement of study
排除标准
- •serious underlying diseases
结局指标
主要结局
titer of neutralizing antibody after COVID-19 vaccination
时间窗: at 12 month after COVID-19 vaccination
semi-quantitative measurement of neutralizing antibody after COVID-19 vaccination
Compare 4 diagnostic ELISA kit after COVID-19 vaccination
时间窗: at 2 month after COVID-19 vaccination
1. measure neutralizung antibody using ELISA kits from 4 different companies 2 months after COVID-19 vaccination 2. investigate correlation coefficient of antibody titer between companies
body weight (Kg)
时间窗: at 2 month after COVID-19 vaccination
correlation between antibody titer and body weight: spearmann's correlation
body mass index (kg/m^2)
时间窗: at 2 month after COVID-19 vaccination
correlation between antibody titer and body weight: spearmann's correlation
次要结局
未报告次要终点
研究者
Su Youn Nam
Assistant professor
Kyungpook National University Hospital