Effect of Exercise on the Neural Response to Food Cues and Energy Intake in Lean and Obese Adolescents
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 发起方
- 试验地点
- 1
- 主要终点
- Neural response to food cues
研究概览
简要总结
Physical exercise has been shown to significantly reduce subsequent energy intake in obese adolescents but not in lean, without altering their appetite feelings. Although previous studies have pointed out the role of gastric peptides in this post exercise nutritional response, some recent work question the role of the neural system in the post exercise drive to eat. This study tends to explore whether or not an acute bout of exercise can affect the neural response to food cues in adolescents, obese or lean.
详细描述
After a medical inclusion, the adolescents will have to realise a DXA to assess their body composition and a submaximal exercise to evaluate their aerobic capacities.
They will have then to enter the laboratory on 2 different occasions in a randomized order from 8am to 330pm: At 8am they will receive a calibrated breakfast. then, at 1045; they will have to complete one of the experimental condition: 1) a cycling exercise or 2) remaining sitting fpr one hour. after the one hour sitting station or the exercise bout, they will be asked to complete a computer task while and electroencephalogram will be recorded. This computer task consists in visual recognition of rare pictures compared to frequent ones (oddball method). at 1215 they will be offered ad libitum meals. At regular intervals through the day, their appetite feelings will be assessed using Visual analogue scales.
Ad libitum energy consumption will be assessed by investigators and recorded for each participants.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Crossover
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 12 Years 至 15 Years（Child）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •12-15 years old
- •BMI defining obesity (Cole et al., 2000)
- •Not being under diet restriction
- •Information and consent forms have to be signed by the adolescent and his legal representative
- •being registered to the national social security system
排除标准
- •Being under medication
- •contraindication to exercise
结局指标
主要结局
Neural response to food cues
时间窗: up to 2 months
The electroencephalogram signals amplitude in response to visual food cues will be the primary outcome, after the exercise (during the exercise condition) and after the sitting position (during the control session)
次要结局
未报告次要终点
研究者
THIVEL David
Research Scientist
Université Blaise Pascal, Clermont-Ferrand