TCTR20190927004招募中2 期
System development of cultivated oral mucosal epithelial transplantation for limbal stem cell deficiency in Thailand
ational Science and Technology Development Agency0 个研究点目标入组 10 人开始时间: 2019年9月27日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 发起方
- 入组人数
- 10
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 Years 至 0 N/A (No limit)（—）
- 性别
- All
入选标准
- •1. Patients with unilateral or bilateral limbal stem cell deficiency (LSCD) from chemical or thermal burns, chronic keratitis, multiple corneal surgeries, and prolonged use of eye drops
- •2. Patients with clinical signs of LSCD at least 180 degrees of the corneal circumference
- •3. Patients diagnosed with LSCD by impression cytology
排除标准
- •1. Patients aged below 18 years
- •2. Patients with severe dry eye (Schirmer's test = 0 mm)
- •3. Patients with uncontrollable glaucoma
- •4. HIV-infected patients
- •5. Patients with hepatitis C virus infection
- •6. Patients with ongoing ocular infection
- •7. Patients with contraindications of ocular surgery or general anesthesia
- •8. Patients with pregnancy
- •9. Patients unable to follow-up
- •10. Patients with non-compliance, physically or mentally
- •Additional exclusion criteria for allo-SLET patients
- •1. Patients with contraindications of immunosuppressive agents or sterioids e.g. uncontrollable diabetes mellitus, ongoing systemic infection, hepatic failure, renal failure, etc.
- •2. Patients allergic to immunosuppressive agents or steroids
研究者
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