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临床试验/NCT07711028
NCT07711028进行中(未招募)不适用

EFFECT of PH on Outcomes of ESWL in Renal Stones

Benha University1 个研究点 分布在 1 个国家目标入组 146 人开始时间: 2026年1月20日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
进行中(未招募)
入组人数
146
试验地点
1
主要终点
Stone free rate

研究概览

简要总结

urolethiasis (kidney stones) is common globally, with recurrence in 50% of patients.

  • Shock Wave Lithotripsy (SWL) is a minimally invasive treatment for stones < 2 cm.
  • Hypothesis: Urine pH might influence SWL success and could be manipulated pre-procedure. Aim of the work is to evaluate the role urine pH on the outcomes of shock wave lithotripsy in renal stones. patients and methods The study will be conducted over 146 patients( with single renal stone < 2 cm) in Urology department of Banha university Hopitals from Dec 2025 till Dec 2026. Exclusions: patients on pH altering drugs, multiple stones,stents. Procedure: SWL Siemens Lithoscope up to 3 sessions per patient. Data collected : Age, BMI, urine pH, specific gravity(SG), stone size, location, Hounsfield unit(HU), skin to stone distance (SSD). Analysis Chi-square& t-test; significance at p<0.05. Results Will be tabulated and statistically analyzed

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Single Group
主要目的
Screening
盲法
None

入排标准

年龄范围
18 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Single renal calculus.
  • Stones less than 2 cm in its maximum diameter.

排除标准

  • Patients receiving any pH-altering medications.
  • Patients have multiple renal stones.
  • Patients have indwelling ureteral stents.

研究组 & 干预措施

Role of urine PH

No Intervention

Role of urine PH in shock wave lithotripsy outcomes in renal stone disease

Other

干预措施: Shock Wave Iithotripsy (Procedure)

Role of urine PH in shock wave lithotripsy outcomes in renal stone disease

Other

干预措施: Extracorporeal shock wave lithotripsy (Procedure)

结局指标

主要结局

Stone free rate

时间窗: Four weeks

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Ahmed Abou Elezz Abdel Fattah

Assistant Professor Dr

Benha University

研究点 (1)

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