For 12-Weeks, Multi-center, Randomized, Double-blind, Parallel Designed, Clinical Study to Evaluate the Ankle Edema Formation of Lodien tablets vs. Norvasc tablets in Female Patients with Essential Hypertension

Hanlim Pharmaceutical0 个研究点目标入组 40 人开始时间: 待定最近更新: 2019年3月11日

适应症

试验速览

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•Patients with essential hypertension (systolic blood pressure > 140 mmHg and/or diastolic blood pressure > 90 mmHg) were eligible. Patients receiving other antihypertensive medications had to discontinue their previous medications and have a blood pressure over 140/90 mmHg and under 180/110 mmHg after the 2 week placebo run-in period.

•secondary hypertension; angina pectoris, myocardial infarction, cerebrovascular disease, or clinically significant arrhythmia within the past 6 months; abnormal laboratory test results (serum creatinine levels > 1.5 times the upper limit of normal, serum aspartate aminotransferase of alanine aminotransferase levels >2 times the upper limit of normal); uncontrolled diabetes mellitus (HbA1c = 9%) or use of insulin; and use of antihypertensive drugs other than the study agents. Women of child-bearing age were required to have a negative urine pregnancy test before enrollment, and must use an acceptable method of birth control.

发起方

Hanlim Pharmaceutical