Nailfold Capillaroscopic Changes in Psoriasis and Its Correlation With Disease Severity
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 100
- 试验地点
- 2
- 主要终点
- Nailfold capillaroscopic abnormalities in psoriasis patients
研究概览
简要总结
The goal of this observational study is to evaluate nailfold capillaroscopic changes in patients with psoriasis and to assess their correlation with disease severity. The study will also explore differences in capillaroscopic findings across different clinical types of psoriasis and skin phototypes (Fitzpatrick classification). The study will include patients diagnosed with psoriasis attending dermatology outpatient clinics. Participants will undergo clinical assessment and nailfold capillaroscopy to detect microvascular changes.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients clinically diagnosed with psoriasis.
排除标准
- •Patients with connective tissue diseases (e.g., systemic sclerosis, SLE)
- •Diabetes mellitus or peripheral vascular disease
- •Current smokers
- •Pregnant or lactating women
- •Recent use of vasodilators or beta-blockers
- •Manual workers exposed to vibrating tools
结局指标
主要结局
Nailfold capillaroscopic abnormalities in psoriasis patients
时间窗: Baseline
Detection and description of nailfold capillaroscopic (NFC) abnormalities in patients with psoriasis.
次要结局
- Variation of nailfold capillaroscopic findings among different clinical types of psoriasis and correlation with disease severity (PASI score).(Baseline)
研究者
Ahmed Hassan Nouh MD
Assistant Professor of Dermatology & Venereology
Al-Azhar University