NCT00600652Unknown不适用
Flow Cytometric Analysis of Glucocorticoid Receptor Using Monoclonal Antibody and Fluoresceinated Ligand Probes in Glucocorticoid-Resistant and -Sensitive Patients
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 150
研究概览
简要总结
Monitoring the GR with a GR-MoAb and FITC-Dex probes by FCM would be useful and convenient in determination GR before the steroid treatment in clinical, especially in steroid resistant states, in order to design more efficient clinical treatment protocols.
详细描述
In order to assess the efficacy of this method, 100 patients with nephrotic syndrome and systemic lupus erythematosus receiving sufficient prednisolone thereafter and 50 age- and sex-matched normal controls will be studied.
研究设计
- 研究类型
- Observational
- 时间视角
- Prospective
入排标准
- 年龄范围
- 15 Years 至 65 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Clinical diagnosis of SLE and NS
排除标准
- •Receiving hormone replacement therapy or had received hormone replacement therapy in three months before start of the study
- •Received drugs or drinks containing alcohol within one month
- •Having symptom such as infection
- •Supersensitivity and endocrine disturbance.
研究者
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