DRKS00025879已完成未知
Investigate the effects of a spermidine supplementation on immune system and inflammatory parameters in old and young adults - ImmuneAge-Study
Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke (DIfE)0 个研究点目标入组 40 人开始时间: 2022年4月28日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized controlled study
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 25 Years 至 90 Years（—）
- 性别
- All
入选标准
- •Young adults: age: 25-40 years; BMI: 20-30 kg/m²; no chronic medication except for oral contraceptives;
- •Old adults: age: 70-90 years; BMI: 20-30 kg/m²;
- •No limitations in ‘’activities of daily living’’;
- •Subjects must be able to consent as defined by law.
排除标准
- •Pregnancy/breastfeeding;
- •Existing or past immune diseases such as leukemia, lymphoma, malignant neoplasms affecting bone marrow and lymphatic system, HIV or AIDS;
- •Self-reported severe or active medical conditions such as arteriosclerosis, advanced cardiac or respiratory disease, such as chronic obstructive pulmonary disease (COPD; GOLD-Stadium =3 (Global Initiative for Chronic Obstructive Lung Disease”-classification)) or heart failure (NYHA =3 (New York Heart Association));
- •Self-reported neurological or mental impairment;
- •Self-reported severe liver, kidney, or metabolic disease, such as liver cirrhosis (Child Pugh Score =2) or kidney disease (Stadium =3);
- •Drug/medication/alcohol dependence;
- •Existing polyamine supplementation;
- •Known intolerances or allergies to wheat germ, gluten, or histamine.
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