Effect of a Point-Of-Care Ultrasound-Driven vs Standard Diagnostic Pathway on 24-Hour Hospital Stay in Emergency Department Patients With Dyspnea - a Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 674
- 试验地点
- 9
- 主要终点
- 24-hour hospital stay
研究概览
简要总结
The POCUS PATHWAY-trial is a multi-center, randomized, investigator-initiated, open labelled, pragmatic, controlled trial of a point-of-care ultrasound-driven diagnostic pathway vs standard diagnostic pathway in dyspneic emergency department patients. The primary outcome will be 24-hour hospital stay and 642 patients will be included. Key secondary outcomes include overall hospital length of stay, image resources, and 72-hour revisits.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Emergency department contact
- •Age ≥ 18 years
- •Chief complaint is Dyspnea
- •Including physician present
排除标准
- •Fulfilling of criteria for coded rapid-response teams (i.e., trauma, surgical or medical emergencies).
- •Prior focused lung or focused cardiac ultrasound in the current emergency department stay
- •Prior enrollment in the trial
- •Unable to consent
- •Non Danish-speaking
研究组 & 干预措施
Point-of-care ultrasound-driven diagnostic pathway
The intervention is focused lung and cardiac ultrasound performed as an extension to physical examinations plus diagnostic decision recommendations based on those test results (a point-of-care ultrasound-driven diagnostic pathway). Final decision on next-line imaging and further diagnostic testing should incorporate history and other physical examinations and will remain upon the treating physicians' discretion.
干预措施: Point-of-care ultrasound-driven diagnostic pathway (Diagnostic Test)
Standard diagnostic pathway
Standard diagnostic pathway will include, but not be limited to, blood samples, blood gases, electrocardiogram, and chest x-ray. Focused lung and cardiac ultrasound cannot be performed while the patients stay in the emergency department.
结局指标
主要结局
24-hour hospital stay
时间窗: From date of hospital admission until the date of first documented hospital discharge, assessed up to 24 hours.
Proportion of patients with a hospital lenght-of-stay of less than 24 hours.
次要结局
- Number of participants with the composite outcome of 72-hour revisits and overall mortality(From date of hospital admission until 72 hours after the date of first documented hospital discharge, assessed up to 3 months.)
- Image resources(From date of hospital admission until the date of first documented hospital discharge, assessed up to 3 months.)
- Hospital length-of-stay(From date of hospital admission until the date of first documented hospital discharge, assessed up to 3 months.)
研究者
Stig Holm Ovesen
MD, Principal Investigator
Aarhus University Hospital