NCT00186394已完成2 期
High Dose Chemotherapy and Allogeneic Hematopoietic Cell Transplantation for Non-Hodgkin's Lymphoma
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 35
- 试验地点
- 2
- 主要终点
- Safety
研究概览
简要总结
To evaluate the role of allogeneic hematopoietic cell transplantation in the treatment of NHL.
详细描述
To determine safety and toxicity of a regimen of high dose chemotherapy with allogeneic peripheral blood progenitor cell transplantation; determine the efficacy of the procedure by following clinical outcomes and quality of life measures; and evaluate graft versus host disease incidence and severity with regimen.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 61 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Morphologically confirmed relapsed non-Hodgkin's lymphoma
- •Age: >18 and <61 years of age
- •Signed informed consent
排除标准
- •Hepatic dysfunction defined by serum transaminases >2.5X normal values
- •Serum creatinine of > 2 mg/dl or creatinine clearance < 60 ml/min
- •Diseases other than non-Hodgkin's lymphoma
- •Prior bone marrow transplant procedure
- •Severe psychological or medical illness
结局指标
主要结局
Safety
Toxicity
Efficacy
次要结局
- Incidence of acute and chronic GVHD
研究者
研究点 (2)
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