Changes in resting Anal Sphincter Pressure following topical application of a combination of Diltiazem and Lignocaine as compared to Topical Diltiazem and Lignocaine alone - a randomized double blind study.

Troikaa Pharmaceuticals Limited0 个研究点目标入组 45 人开始时间: 待定最近更新: 2021年11月24日

试验速览

暂无简介。

•1. Adult patients of either sex aged 18 - 60 years.
•2. Patients diagnosed with chronic anal fissure
•3. Patients having symptoms (pain) present for a minimum of 6 weeks despite standard therapy (diet, laxatives, Sitz-baths)

•1. Patients having anal fistulas or anal fissure of various causes such as Crohn disease, anal suppuration, abscesses,
•2. Patients with associated acute haemorrhoidal attacks
•3. Patients having anal or perianal malignancy
•4. Patients who have been surgically treated previously
•5. Patients on oral CCBs./ nitrates/ vasodilators
•6. Patients who are on topical therapy with lignocaine/ steroids/ calcium channel blockers
•7. Known hypersensitivity to diltiazem
•8. Pregnant women /lactating mother
•9. Patients with HIV infection
•10. Pregnant women /lactating mother

发起方