Initial Versus Delayed Operation for Treatment of Complicated Appendicitis In Children
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 23
- 试验地点
- 1
- 主要终点
- cost effectiveness
研究概览
简要总结
To determine the most cost effective way to treat children with perforated appendicitis we will randomize all children presenting with perforated appendicitis to initial operation, with in 24 hours of admission, or to initial antibiotics, with or without percutaneous drainage, and subsequent interval appendectomy after 8 weeks. Our outcomes will include cost, complications, length of stay, and quality of life measures.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 2 Years 至 17 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 2-17 with a diagnosis of perforated appendicitis
排除标准
- •Age <2 and >18
- •Pregnancy
- •Immunocompromise
研究组 & 干预措施
Initial appendectomy
children with complicated appendicitis will undergo initial appendectomy
干预措施: Initial appendectomy (Procedure)
Interval appendectomy
children with complicated appendicitis will undergo initial antibiotic treatment followed by an interval appendectomy
干预措施: Interval appendectomy (Procedure)
结局指标
主要结局
cost effectiveness
时间窗: 3 months post entry into the study
次要结局
未报告次要终点
研究者
Steven W. Bruch
Clinical Assoicate Professor
University of Michigan