Microbiological Screening Of Malignant Otitis Externa Patients Presenting at Sohag University Hospitals
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Number and percentage of bacterial and fungal isolates resistant to each antibiotic tested at enrollment
研究概览
简要总结
This is a prospective study to identify the bacterial and fungal organisms causing Malignant Otitis Externa (MOE) in patients presenting to Sohag University Hospitals. Ear swabs will be collected from patients diagnosed with MOE and sent to the microbiology lab for culture and sensitivity testing. The goal is to determine the most common pathogens and their antibiotic resistance patterns to help doctors choose the best treatment.
详细描述
Malignant Otitis Externa is a severe infection of the external ear canal that can spread to the skull base. It is most common in elderly diabetic patients. There is limited data about the microbiological profile of MOE patients in Upper Egypt.
Objectives:
- To identify the bacterial and fungal pathogens isolated from patients with MOE at Sohag University Hospitals.
- To determine the antibiotic susceptibility patterns of the isolated organisms.
Methods:
This is a prospective cross-sectional study. Patients diagnosed with MOE in the ENT department at Sohag University Hospitals will be included. An ear swab will be taken from each patient under sterile conditions and sent to the microbiology laboratory. Samples will undergo culture, identification, and antibiotic sensitivity testing according to standard lab protocols. Patient demographic data and clinical findings will also be recorded.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients clinically diagnosed with MOE based on severe otalgia, external auditory canal inflammation ± granulation tissue.
- •Patients with risk factors such as DM, Immunocompromised patients.
排除标准
- •Post-operative ear cases (recent ear surgery).
- •Patients with external auditory canal tumors.
- •Patient refusal
结局指标
主要结局
Number and percentage of bacterial and fungal isolates resistant to each antibiotic tested at enrollment
时间窗: At time of enrollment, from July 2026 to July 2027
Measure: Antibiotic susceptibility testing will be performed on all isolates obtained from patients with Malignant Otitis Externa according to CLSI guidelines. Metric: Count and percentage of resistant isolates for each antibiotic.
次要结局
- Number and percentage of microbial isolates with antibiotic and antifungal resistance at enrollment(At time of enrollment, from July 2026 to July 2027)
研究者
Omar Ashraf Mohamed
Prof. Mohamed AbdElkader Ahmed
Sohag University