Pre-Sleep Creatine Enhances Anaerobic Power in Recreationally Active Females
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 24
- 试验地点
- 1
- 主要终点
- Average Power Output (Watts) - 30-Second Wingate Test
研究概览
简要总结
This study is a randomized, double-blind, placebo-controlled trial designed to examine the effects of pre-sleep creatine monohydrate supplementation on anaerobic performance and muscle damage markers in recreationally active females. Participants will be randomly assigned to receive either 5 grams of creatine monohydrate or a placebo 30 minutes before sleep for seven consecutive days. Anaerobic performance will be assessed using the Wingate Anaerobic Test, evaluating peak and average power output and fatigue index. Blood samples will be collected before and after the supplementation period to analyze markers of muscle damage, including creatine kinase and lactate dehydrogenase. This study aims to provide insight into the efficacy of short-term, time-specific creatine supplementation for enhancing performance and recovery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
盲法说明
Neither the participants nor the investigators know which intervention the participant is receiving.
入排标准
- 年龄范围
- 18 Years 至 25 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Female, aged 18 to 25 years
- •Recreationally active (engaging in structured resistance training 3-4 times per week for the past 6 months)
- •Regular menstrual cycles (used for scheduling purposes)
- •Able and willing to provide informed consent
- •Agreement to maintain normal diet and training routines throughout the study
排除标准
- •History of musculoskeletal injury affecting lower or upper limbs within the past 6 months
- •Known allergy or intolerance to creatine or maltodextrin
- •Use of performance-enhancing substances or supplements within the last 30 days
- •Use of recovery modalities such as massage, cryotherapy, or compression garments during the study period
- •Current use of anti-inflammatory medication
- •Pregnancy or breastfeeding
- •Inability to comply with study protocol or scheduled assessments
研究组 & 干预措施
Placebo Supplementation
Participants will receive 5 grams of a placebo powder (maltodextrin), visually identical and similarly flavored to the creatine supplement, 30 minutes before sleep each night for 7 days.
干预措施: Placebo (Maltodextrin) (Dietary Supplement)
Creatine Monohydrate Supplementation
Participants will receive 5 grams of creatine monohydrate powder dissolved in water, flavored with a sugar-free agent, 30 minutes before sleep each night for 7 days.
干预措施: Creatine Monohydrate (Dietary Supplement)
结局指标
主要结局
Average Power Output (Watts) - 30-Second Wingate Test
时间窗: Baseline and post-intervention (Day 0 and Day 7)
Average anaerobic power output will be calculated across the 30-second Wingate cycling test.
次要结局
- Peak Power Output (Watts) - Wingate Test(Baseline and post-intervention (Day 0 and Day 7))
- Fatigue Index (%) - Wingate Test(Baseline and post-intervention (Day 0 and Day 7))
- Serum Creatine Kinase (CK) Activity(Baseline and 24 hours post Wingate Test (Day 0 and Day 8))
- Serum Lactate Dehydrogenase (LDH) Activity(Baseline and 24 hours post Wingate Test (Day 0 and Day 8))
研究者
caglar soylu
Asisstant Professor
Ankara Yildirim Beyazıt University