Effects of Different Progesterone Containing Contraceptive Methods on Safety and Endogenous Progesterone Level
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Assess the effect of different progesterone containing contraceptive methods on safety and endogenous progesterone level
研究概览
简要总结
The aim of this study is to assess the effect of different progesterone containing contraceptive methods on safety and endogenous progesterone level
详细描述
Progestogen-only' contraceptives are presented as injections, implants, oral formulations, hormone-releasing intrauterine methods and emergency contraceptives. These substances could be used by females who are breastfeeding or have other contraindications to estrogen treatment, including those who are immediately postpartum, have thalassemia, sickle-cell disease, gallbladder disease, or currently experiencing thrombo-embolic disorders, valvular heart disease, ischemic heart disease.
Intrauterine, injectable methods and contraceptive implants named as long-acting reversible contraceptives (LARC) are the more efficient reversible contraceptive approaches are highly effective, longer-acting contraceptive methods levels.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •80 healthy fertile females
- •20-35 years
- •With normal menstrual history
- •Had at least one offspring after spontaneous pregnancy
排除标准
- •Any disease affects uterus (uterine tumors fibroids, endometriosis, prolapse, or tuberculosis).
- •Ovarian tumors
- •submucous myoma
- •irregular menstrual cycle
- •past or family history of breast disease
- •Diabetic patients,
- •medication affecting reproductive or metabolic functions.
- •endometrial thickness <7 mm on the secretory transformation day
- •history of spontaneous abortions
- •history of embryo transfer failure on over three occasions
- •Patients had cortisol medications
- •patients who received radiological treatment
结局指标
主要结局
Assess the effect of different progesterone containing contraceptive methods on safety and endogenous progesterone level
时间窗: Six mounths
The effect of different progesterone containing contraceptive methods on safety and endogenous progesterone level will be recorded
次要结局
未报告次要终点
研究者
Ahmed Ossman
Assistant Professor of Obstetrics and Gynecology Department,Faculty of Medicine,Tanta University
Tanta University