Evaluation of Drug Overdose Poisoning Cases and Indications for ICU Admission
试验速览
- 阶段
- 不适用
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Evaluation of drug overdose cases presented to Assiut university hospitals' adults and pediatric E.D.
研究概览
简要总结
- Evaluation of drug overdose cases presented to Assiut university hospitals' adults and pediatric emergency departments (EDs) in one year period.
- Evaluation the role of intensive care unit (ICU) admission in these cases and possible scoring system for common groups of drug overdose.
详细描述
Poisoning is a medical emergency representing a health problem all over the world with an incidence rate that is variable from one place to another.
The nature of poison used varies in different parts of the world and may vary even in different parts of the same country.
The pattern of poisoning within a country depends on several factors such as the accessibility of various poisons, socio-economic status of the population, religious and cultural influences and drug prescription manners.
Drug overdose continues to be the most common cause of acute poisoning all over the world. An estimated 2 to 5 million poisonings and drug overdoses occur annually in the United States of America.
Overdose is the most common manifestation of deliberate self-harm behavior, and is a common cause of presentation to hospital Emergency Departments (EDs). It starts to get global attention due to its higher rate of morbidity and mortality in spite of being a preventable cause of death.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients admitted or transferred to Assiut university hospitals' adults and pediatric EDs, with history of drug overdose intoxication within 24 hours prior to admission (single or multiple drug ingestions).
- •Patients admitted or transferred to Assiut university hospitals' adults and pediatric EDs, with clinical signs and symptoms of drug overdose intoxication on examination.
- •Patients admitted or transferred to Assiut university hospitals' adults and pediatric EDs, with blood and/or urine toxicology screens demonstrated the presence of non-prescribed, illicit drugs or inappropriately elevated levels of prescribed or over the-counter medications.
排除标准
- •Patients admitted or transferred to Assiut university hospitals' adults and pediatric EDs, with history of drug overdose intoxication more than 24 hours.
- •Patients admitted or transferred to Assiut university hospitals' adults and pediatric EDs, with history of non-drug intoxication, e.g insecticides poisoning
结局指标
主要结局
Evaluation of drug overdose cases presented to Assiut university hospitals' adults and pediatric E.D.
时间窗: One year
A) Sheet includes the following items:- 1. Demographic data: Gender, Age, Marital status, Residence, Occupation, Special habits: smoking, drug abuse. 2. Data regarding overdosed drug: Type, form, dose and method of administration and mode of exposure 3. Symptoms of intoxication. B) Complete clinical examination C) Investigations: 1. Routine: ABG, ECG, Electrolytes 2. Specific Drug level, drug screening test in urine
次要结局
- Evaluation of the indications of intensive care unit (ICU) admission in drug overdose cases.(one year)
研究者
Peter Eissa Saad
Demonstrator at Forensic and clinical toxicology department
Assiut University