Etude Multicentrique en Population de la susceptibilité génétique à Faire Une Mort Subite
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 2,332
- 试验地点
- 1
- 主要终点
- Frequency of Single Nucleotide Polymorphism (SNP) across the entire genome
研究概览
简要总结
Sudden death is a major problem in industrially developed countries. Despite a decline in ischemic heart disease mortality and the progress has been made in resuscitation, treatment of sudden death victims is frequently unsuccessful. the ideal solution would be to prevent the disease process that causes the initial episode of cardiac arrest. Parental sudden death is an independent risk factor for sudden death. So, detect a gene predisposing to sudden death may help provide better identification of subjects at high risk of cardiac arrest. This research is a genetic study of sudden cardiac death, recruited 2000 subjects in out-of-hospital cardiac arrest.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 75 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Aged from 18 to 75 years
排除标准
- •People not free
- •Inhospital subjects
- •Death by other disease
- •Violent death
研究组 & 干预措施
1
case of out-of-hospital cardiac arrest
2
cases of MI
3
controls without coronary disease
结局指标
主要结局
Frequency of Single Nucleotide Polymorphism (SNP) across the entire genome
时间窗: Day 1
DNA extracted from blood cells
次要结局
未报告次要终点
