NCT01403467已完成4 期
Impact of Continuous Positive Airway Pressure on the Treatment of Acute Asthma Exacerbation
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 86
- 试验地点
- 2
- 主要终点
- an improvement in PEFR, as % predicted
研究概览
简要总结
This current study aimed to demonstrate the effectiveness of the addition of CPAP to the current conventional therapy in terms of airway obstruction improvement in acute asthma patients.
详细描述
Continuous positive airway pressure (CPAP) is widely used in providing ventilator support. However, its role in an acute asthmatic attack is uncertain. The purpose of this study was to compare the efficacy of CPAP when used in addition to conventional therapy with conventional therapy alone in the management of acute asthma exacerbation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 19 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •aged over 18 years
- •known asthmatic patients visiting ED with acute exacerbation
- •had given their written informed consent.
排除标准
- •smoking history
- •chronic obstructive pulmonary disease
- •required intubation
- •instability of hemodynamic or arrhythmia
- •unable to perform PEFR
- •facial abnormality
- •pulmonary infiltration
- •pregnancy.
结局指标
主要结局
an improvement in PEFR, as % predicted
时间窗: 75 mins
次要结局
未报告次要终点
研究者
研究点 (2)
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