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临床试验/NCT07729631
NCT07729631已完成不适用

Study to Establish Glycaemic Response to the Ingestion of Vegetable Smoothies Expressed as Glycaemic Index Following Best Practice Guidelines

University of Bath1 个研究点 分布在 1 个国家目标入组 16 人开始时间: 2025年10月22日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
16
试验地点
1
主要终点
Glycaemic indices for 2 test drinks measured using capillary blood samples

研究概览

简要总结

Glycaemic responses to carbohydrates ingested as fruit and vegetables may vary depending on factors inherent to the fruit or vegetable, and on the type of sugar. The aim of this project is to investigate the glycaemic responses to two new fruit and vegetable smoothies, and to establish the glycaemic index for each product relative to a glucose reference. Participants will undertake 4 postprandial tests with 2 different test drinks following best practice guidelines for glycaemic index testing. The test drinks (GREEN and RED) will be matched for carbohydrate to the glucose reference (CONTROL) which will be sampled two times. Fingerstick capillary blood sampling will measure glucose concentrations. These data will provide insight into how differing formulations can alter the glycaemic responses to fruit and vegetable drinks.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Basic Science
盲法
None

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age: 18-65 years
  • Body mass index 18-30 kg/m2

排除标准

  • diagnosis of any form of diabetes
  • intolerances or allergies to any of the study procedures (e.g. fructose/inulin intolerance)
  • Fructose malabsorption
  • Inborn errors of fructose metabolism (e.g. fructokinase deficiency, aldolase B deficiency, fructose-1,6-bisphosphatase deficiency)
  • pregnant or lactating
  • any condition that could introduce bias to the study (e.g. diagnoses of lipid disorders, including cardiovascular disease, or therapies that alter lipid or glucose metabolism, such as statins or niacin).

结局指标

主要结局

Glycaemic indices for 2 test drinks measured using capillary blood samples

时间窗: 120 minutes

Glycaemic indices \[2-hour incremental area under the glucose curve (mmol/L-1x120 minutes) for each of the 2 test drinks relative to mean value of control conditions (CONTROL, REPLICATE CONTROL), expressed as a percentage\] in capillary blood samples

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Emma Greatorex Brooks

PhD Researcher

University of Bath

研究点 (1)

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