Study to Establish Glycaemic Response to the Ingestion of Vegetable Smoothies Expressed as Glycaemic Index Following Best Practice Guidelines
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 16
- 试验地点
- 1
- 主要终点
- Glycaemic indices for 2 test drinks measured using capillary blood samples
研究概览
简要总结
Glycaemic responses to carbohydrates ingested as fruit and vegetables may vary depending on factors inherent to the fruit or vegetable, and on the type of sugar. The aim of this project is to investigate the glycaemic responses to two new fruit and vegetable smoothies, and to establish the glycaemic index for each product relative to a glucose reference. Participants will undertake 4 postprandial tests with 2 different test drinks following best practice guidelines for glycaemic index testing. The test drinks (GREEN and RED) will be matched for carbohydrate to the glucose reference (CONTROL) which will be sampled two times. Fingerstick capillary blood sampling will measure glucose concentrations. These data will provide insight into how differing formulations can alter the glycaemic responses to fruit and vegetable drinks.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age: 18-65 years
- •Body mass index 18-30 kg/m2
排除标准
- •diagnosis of any form of diabetes
- •intolerances or allergies to any of the study procedures (e.g. fructose/inulin intolerance)
- •Fructose malabsorption
- •Inborn errors of fructose metabolism (e.g. fructokinase deficiency, aldolase B deficiency, fructose-1,6-bisphosphatase deficiency)
- •pregnant or lactating
- •any condition that could introduce bias to the study (e.g. diagnoses of lipid disorders, including cardiovascular disease, or therapies that alter lipid or glucose metabolism, such as statins or niacin).
结局指标
主要结局
Glycaemic indices for 2 test drinks measured using capillary blood samples
时间窗: 120 minutes
Glycaemic indices \[2-hour incremental area under the glucose curve (mmol/L-1x120 minutes) for each of the 2 test drinks relative to mean value of control conditions (CONTROL, REPLICATE CONTROL), expressed as a percentage\] in capillary blood samples
次要结局
未报告次要终点
研究者
Emma Greatorex Brooks
PhD Researcher
University of Bath
