Stress-motivated Alcohol Use as a Value-based Decision-making Process
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 160
- 试验地点
- 1
- 主要终点
- Proportion of choices for alcoholic over non-alcoholic drinks.
研究概览
简要总结
The goal of this experimental study is to improve our understanding of the effects of stress on the decision to consume (more) alcohol in regular drinkers. The main question[s] it aims to answer are:
- Does psychological stress affect the decision to consume (more) alcohol?
- How does psychological stress affect the decision to consume (more) alcohol? Participants will be randomly assigned to one of four conditions (stress alcohol, stress no alcohol, no stress alcohol, no stress no alcohol) and complete a value-based decision-making task twice (once before and once after the manipulations).
详细描述
In this study, the investigators will explore whether and how the decision between consuming an alcoholic or non-alcoholic drink is influenced by a stressful event and by being already intoxicated.
Behavioral data:
Our first set of hypotheses tests whether the decision is influenced by stress and alcohol intoxication:
H1a: Stress affects the decision between alcoholic and non-alcoholic drinks, so that participants in the stress conditions choose alcoholic over non-alcoholic drinks more often compared to participants in the no stress conditions.
H1b: Alcohol intoxication does not affect the decision between alcoholic and non-alcoholic drinks.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 21 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Drinking alcohol at least once a week
- •Consuming 4 (female) or 5 (male) drinks in one occasion at least once a month
排除标准
- •Currently pregnant or trying to become pregnant
- •Past or current diagnosis of an anxiety disorder, such as Generalized Anxiety Disorder or Post-Traumatic Stress Disorder
- •Past or current treatment for alcohol use
- •Past or current medical condition that contraindicates alcohol use
- •Past or current reaction to alcohol that contraindicates alcohol use
- •Past or current medication that contraindicates alcohol use
研究组 & 干预措施
Stress alcohol
These participants will undergo a stress induction and receive alcoholic beverages to raise their BAC to .06%
干预措施: Stress (Other)
Stress alcohol
These participants will undergo a stress induction and receive alcoholic beverages to raise their BAC to .06%
干预措施: Alcohol (Other)
Stress no alcohol
These participants will undergo a stress induction and receive non-alcoholic beverages
干预措施: Stress (Other)
No stress alcohol
These participants will undergo a neutral induction and receive alcoholic beverages to raise their BAC to .06%
干预措施: Alcohol (Other)
No stress no alcohol
These participants will undergo a neutral induction and receive non-alcoholic beverages
结局指标
主要结局
Proportion of choices for alcoholic over non-alcoholic drinks.
时间窗: 5 minutes
Each participant will complete a two alternative forced-choice task in which they make repeated decisions between alcoholic and non-alcoholic drinks.
次要结局
未报告次要终点
研究者
Jonas Dora
Principal Investigator
University of Washington