JPRN-UMIN000005219已完成2 期
Randomized phase II trial evaluating trastuzumab + capecitabine (HX) or lapatinib + capecitabine (LX) in HER2-positive metastatic breast cancer patients previously treated with trastuzumab and taxanes - WJOG6110B: Early switch to Lapatinib versus Trastuzumab beyond Progression (ELTOP) study
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 110
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 ot applicable（—）
- 性别
- Female
入选标准
- 未提供
排除标准
- •1) History of other malignancy,except for curatively treated carcinoma in situ or intramucosal carcinoma (Subjects with other malignancies who have been disease-free for at least 5 years are eligible.) 2) Active infection under treatment 3) Concurrent serious disease or condition 4) Pulmonary fibrosis or interstitial pneumonitis by chest x-ray 5) Symptomatic brain metastases or carcinomatous meningitis 6) History of serious allergic reactions 7) Concurrent continuous systemic treatment with medications listed below: Steroids Warfarin CYP3A4 inducing anticonvulsants Rifampicin Azole antifungals 8) Concurrent serious psychiatric disorder 9) Pregnant or lactating females or subjects of childbearing potential who do not agree to use adequate contraception 10) HBsAg-positive
研究者
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