Improving Clinical Staging for Muscle Invasive Bladder Cancer Through Molecular Profiling and Improved Imaging
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 16
- 试验地点
- 1
- 主要终点
- Detection Improvement of Cancer Outside of the Bladder
研究概览
简要总结
The goal of this research study is to improve detection of cancer outside of the bladder through genetic testing and improved imaging.
详细描述
If participant agrees to take part in the study, a piece of the tumor that is removed during the biopsy will be collected for research purposes. The tissue will be sent to the laboratory for genetic testing.
If they have had a computed tomography scan (CT scan) or magnetic resonance imaging scan (MRI) recently, information collected from the scan will be collected. If they have not had one recently, they will have an MRI with contrast as part of this study. They will receive a separate consent form for this MRI scan.
The results of the test will be given to their doctor, but the results will not be used to decide their treatment.
After they have surgery, information will be collected from their medical records, such as their diagnosis.
Length of Study:
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with biopsy proven bladder cancer of any age will be eligible for enrollment.
排除标准
- •Contraindication to pelvic MRI (metallic implants/hardware, claustrophobia)
- •Participants who have previously received chemotherapy as part of multimodal therapy.
结局指标
主要结局
Detection Improvement of Cancer Outside of the Bladder
时间窗: 4 weeks
Improved cross sectional imaging with pelvic MRI, and biopsy specimen molecular profiling used to identify muscle invasive bladder cancer (noc-MIBC). Analysis to determine biologic subtypes which will then be correlated with final pathology, identifying the subtype(s) associated with noc-MIBC.
次要结局
未报告次要终点