Turkish Validity and Reliability Study of the MoCA-B Test
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 166
- 试验地点
- 1
研究概览
简要总结
This study aimed to evaluate the validity, reliability, and diagnostic accuracy of the Turkish version of MoCA-B in distinguishing healthy controls, mild cognitive impairment (MCI), and dementia patients within a low-education population.
详细描述
The prevalence of dementia is steadily increasing, and recognizing cognitive impairment at an early stage-especially during mild cognitive impairment (MCI), before full diagnostic criteria for dementia are met-is crucial. Cognitive screening tools used in individuals with low educational levels often fail to detect MCI. The illiterate version of the Mini-Mental State Examination (MMSE) is insufficient for identifying MCI and early dementia, resulting in delayed diagnosis. The MoCA-Basic (MoCA-B), adapted for low-educated populations and translated into Turkish, has not undergone a validation and reliability study; therefore, it is not routinely used in clinical practice. This study aimed to evaluate the validity and reliability of the Turkish MoCA- B in detecting MCI and dementia, and to compare its diagnostic performance with the MMSE and the Clinical Dementia Rating (CDR).
This study included 55 patients with MCI, 56 with dementia, and 55 healthy controls (total n=166) who presented to the Dementia and Neurology Clinics of Antalya Training and Research Hospital between January 2024 and November 2025. After a detailed mental status examination, participants underwent MoCA-B, MMSE (illiterate version), and CDR assessments. Internal consistency was measured using Cronbach's alpha, and test-retest reliability using the intraclass correlation coefficient (ICC). Group differences were analyzed with one-way ANOVA and Tukey post hoc testing. Correlations between MoCA-B, MMSE, and CDR were evaluated with Pearson correlation. Diagnostic accuracy was assessed through ROC analyses, and optimal cut- off values were determined using the Youden index.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 50 Years 至 100 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age 50-100 years
- •Presented with memory complaints and were evaluated in the Neurology/Dementia outpatient clinics of Antalya Training and Research Hospital (Jan 2024-Nov 2025)
- •Low educational attainment (illiterate to primary school level)
- •Provided informed consent
排除标准
- •Active psychiatric disorders / active psychopathology
- •Intracranial mass lesions
- •Secondary causes of dementia
- •Severe medical conditions affecting cognition
- •History of traumatic brain injury
研究者
Ali Riza Gunduz, MD
MD
Antalya Training and Research Hospital
