Prevalence of Helicobacter Pylori in Patients With Acne Vulgaris
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- H.pylori infection
研究概览
简要总结
The objective of the study is to investigate prevalence of H.Pylori infection among acne vulgaris patients.
详细描述
The study included patients with acne vulgaris and healthy control participants. The study recruited both sexes, all grades of acne, adolescents and young adults.
All patients were subjected to complete history, general and skin examination Acne vlugaris Patients were classified into mild, moderate and severe according to the classification of American Academy of dermatology for acne vulgaris.
Detection of H. pylori infection:
Blood and stool samples were taken from each participant and was directly transferred to laboratory for detection of H. Pylori antigen and antibody.
An enzyme-linked immune sorbent assay (ELISA) was used for quantitative assessment of IgG antibodies against H.Pylori in human serum.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 12 Years 至 60 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Acne vulgaris patients
- •Healthy volunteers (control)
排除标准
- •Patients with a history of drug intake that affects H. Pylori such as proton-pump inhibitors, clarithromycin, tetracyclines, amoxicillin or metronidazole within previous two weeks were excluded.
结局指标
主要结局
H.pylori infection
时间窗: one year
Prevalence of H.pylori infection among acne group and control group
次要结局
未报告次要终点
研究者
Dina Ali
Resident physician, Department of Dermatology, Sohag Educational Hospital
Sohag University