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临床试验/NCT07578233
NCT07578233已完成不适用

Multiparametric MRI for Bladder Cancer: Validation of VI-RADS for the Detection of Muscle Invasive Bladder Cancer

Ain Shams University1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2024年8月1日最近更新:

试验速览

阶段
不适用
状态
已完成
入组人数
60
试验地点
1

研究概览

简要总结

This research aimed to determine how accurately multiparametric magnetic resonance imaging (MRI), when interpreted using the VI-RADS scoring system, can distinguish between invasive and non-invasive bladder cancer.

详细描述

Bladder cancer (BC) is among the most widespread malignancies needing management. The majority of bladder cancers are urothelial cell carcinomas, which are further classified histologically into low-grade and high-grade categories.

Multiparametric magnetic resonance imaging (mpMRI), a recent advancement in MRI technology, combines functional sequences like DWI and DCE-MRI with anatomical T1- and T2-weighted images. This integrated approach enhances tumor detection and staging accuracy, aids in post-therapy response monitoring, and facilitates the identification of local disease recurrence.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Both sexes.
  • Patients with bladder masses diagnosed through ultrasound, computed tomography, or magnetic resonance imaging (MRI), who were scheduled for cystoscopy.

排除标准

  • Contraindications to MRI (such as metallic prostheses or pacemakers).
  • Contraindications to Transurethral Resection (like unfitness for anesthesia or urethral strictures).
  • Elevated serum creatinine levels (precluding IV contrast-enhanced imaging).

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Islam Mohamed Mohamed

Resident of Urology, Ain Shams University, Cairo, Egypt.

Ain Shams University

研究点 (1)

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