Observational, Retrospective, Multi-center Study for Therapeutic Practice Pattern of Lipid-lowering Drug and Its Effect on Parameters in Dyslipidemia of Type 2 Diabetes.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- Variation of the Lipid parameter pattern patients who are treated by lipid-lowering drug.
研究概览
简要总结
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Target disease: Patients with combined dyslipidemia accompanied by type 2 diabetes who has done exogenous visit or hospitalization from Jan 2010 to June 2014.
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Study objective:
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The objective of this study is to Identifying the lipid parameter variation when treating patients who have dyslipidemia of type 2 diabetes for 3±1 months.
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After treating patients who have dyslipidemia of type 2 diabetes for 3±1 months, identifying the reason why changing method of drug dosage and pharmacotherapy.
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If the drug dosage and pharmacotherapy have been changed, Identifying the lipid parameter variation when treating patients by altered drugs for 3±1 months,
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 20 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Among the patients, who has been hospitalized or visited the Outpatient Department OPD, who has dyslipidemia of type 2 diabetes.
- •Patients have the result of lipid parameter test at baseline and after lipid-lowering drug for at least 3 months.
- •Patients who have the result of lipid paraneter test (LDL-C ≥100mg/dL, TG ≥150mg/dL) at baseline.
- •Patients who have no received lipid lowering drug fr at least 2 months prior to the baseline.
- •Patients' age were > 20 years and <75 year.
排除标准
- •Patients who ahs HbA1c≥9%
- •Patients who have no the result of lipid parameter test at baseline and at baseline and after lipid-lowering drug for at least 3 months
- •Patients who have history of drug discontinuation by incresed liver enzyme or rhabdomyolysis.
- •Patients received lipid-lowering drug and TZD(Thiazolidinediones) in study period
- •Renal abnormality
- •Alcoholism or Alcohol abuse
- •Patients treated by Steroids.
- •Pregnant or lactating woman
- •Patients who are judged as not suitable for this study by Investigator.
结局指标
主要结局
Variation of the Lipid parameter pattern patients who are treated by lipid-lowering drug.
时间窗: Over 3±1 months
Increasing LDL-C + Triglyceride(TG)Decreasing HDL-C + Increasing TG
次要结局
- The reason why changed drug dosage and pharmacotherapy after patients taken lipid-lowering drug.(Over 3±1 months)
- Variation for lipid parameter when the patients who are treated for 3±1 months by lipid-lowering drug.(Over 3±1 months)