The Evaluation of Advanced Ultrasonography Applications in the Assessment of Transplanted Kidney Complications
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Peak systolic velocity (cm/s).
研究概览
简要总结
This study evaluates the role of advanced US technology in assessing renal transplants as screening tools such as 3D Ultrasound, Ultrasound SWE, and MFI besides current ultrasound conventional metheds.
详细描述
This study will focus on monitoring renal after transplantation using all US advanced technology.
Aim one will concentrate on the 3D US in assessing artery stenosis (TRAS) compared to the gold standard.
Aim two focuses on will concentrate on Ultrasound elastography in assessing renal stiffness.
Aim three will compare US colour modes such as PD, CD and MFI to assess renal perfusion in three groups.
Duration: 18 Months; participants will have a patient information sheet; once they are happy to participate, consent will be obtained.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Peak systolic velocity (cm/s).
时间窗: 12 weeks
Pean of the blood flow velocities in the artery/ vein peak systolic velocity ≥200 cm/s velocity difference between pre- and post-stenotic segments of 2:1
Resistive Index (RI).
时间窗: 12 weeks
An RI less than 0.7 to 0.8 is considered normal, more than that it is indicator of transplant dysfunction.
Peak systolic velocity ratio (PSVR).
时间窗: 12 weeks
High velocity flow at the stenosis site divided by a reference velocity (normal before stenosis)
次要结局
- Volumetric stenosis.(12 weeks)
- 3D GSM.(12 weeks)