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临床试验/NCT01401725
NCT01401725已完成不适用

Electronic Strategies to Enhance Venous Thromboprophylaxis in Hospitalized Medical Patients

McMaster University6 个研究点 分布在 1 个国家目标入组 600 人开始时间: 2011年4月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
600
试验地点
6
主要终点
Proportion of hospitalized medical patients who are appropriately managed for VTE prophylaxis

研究概览

简要总结

Venous thromboemboli (VTE) are abnormal blood clots that commonly form in the blood vessels of the legs or lungs. They can block normal blood flow, damage organs, and even cause death. The risk of VTE is increased in people who are sick or immobile. VTE is the most common preventable cause of death in hospitalized patients, and its VTE prevention should be a top patient safety priority. Though there is good evidence that injectable blood thinners and/or compression stockings can prevent VTE, over 30% of hospitalized medical patients in Hamilton, Ontario receive inappropriate prevention. Hamilton Health Sciences Corporation is in the process of introducing "electronic order sets" - computer programs that help doctors order medications and other healthcare interventions for their patients. The investigators would like to study if these electronic order sets can help improve the rate of appropriate VTE prevention in hospitalized medical patients. The investigators will examine the rate before and after the introduction of electronic order sets at the Juravinski Hospital and the Hamilton General Hospital. Doctors at the Hamilton General Hospital will also get to use an additional computer program, called a computerized decision support system (CDSS), that helps them decide on the best strategy to prevent VTE in individual patients. The rates of VTE prevention at each hospital will be compared to each other, and to the rates at St. Joseph's Healthcare Hamilton, which will receive neither the order sets nor the CDSS.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Parallel
主要目的
Prevention
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adult patients at least 18 years of age
  • Hospitalization on a general internal medicine ward

排除标准

  • Receiving therapeutic anticoagulation at time of hospitalization

结局指标

主要结局

Proportion of hospitalized medical patients who are appropriately managed for VTE prophylaxis

时间窗: Participants will be followed for the duration of their hospital stay on a medical ward, an expected average of 5 days

'Appropriate management' is defined as: (i) appropriate non-receipt of any form of prophylaxis when the patient has no VTE risk factors; (ii) appropriate receipt of pharmacologic prophylaxis when VTE risk factors are present and the patient has no contraindications for pharmacologic prophylaxis; or (iii) appropriate receipt of mechanical prophylaxis, when VTE risk factors are present and the patient has contraindications for pharmacologic prophylaxis.

次要结局

  • Major bleeding(Participants will be followed for 30 days, from the date of hospital admission)
  • Hospital-acquired venous thromboembolism(Participants will be followed for 30 days, from the date of hospital admission)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Menaka Pai

Assistant Professor

McMaster University

研究点 (6)

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