ACTRN12607000157471终止2 期
Does Heparin improve survivial in severe sepsis? A pilot feasability study
Dr Megan S Robertson0 个研究点目标入组 40 人开始时间: 2007年3月6日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 终止
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 ot stated（—）
- 性别
- All
入选标准
- •1. Diagnosis of severe sepsis 2. Patients able commence study treatment within 24 hours of fulfilling inclusion criteria. 3. Informed consent obtained from the patient or next of kin/legal surrogate.
排除标准
- •1. Patient is receiving continued full anticoagulation treatment for any other reason with either unfractionated heparin (UFH) or coumarin agents2. Patients with contra-indication to low dose UFH or fondaparinux including intracranial haemorrhage, active bleeding or heparin induced thrombocytopaenia(HIT) in the past 3 months.3. Patients with prior adverse reaction to UFH or fondaparinux4. Patients with organ dysfunction due to sepsis present for more than 24 hours5. Patients not for full active treatment, except presence of DNR order.6. Patients not expected to survive 28 days due to underlying or comorbid condition.7. Patient is moribund with death or brain death expected within 24 hours.
研究者
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