跳至主要内容
临床试验/CTRI/2021/06/034065
CTRI/2021/06/034065尚未招募不适用

Cardiovascular disease manifestations with special emphasis on myocarditis-in moderate to severe COVID-19 patients undergoing treatment in the ccu of a tertiary care hospital in West Bengal India

Dr Swati Datta1 个研究点 分布在 1 个国家目标入组 382 人开始时间: 2021年9月6日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
382
试验地点
1
主要终点
1. Need for mechanical ventilation

研究概览

简要总结

Hospitalized patients admitted with fever, cough, sore throat and/or dyspnoea who will be tested positive for SARS-COV-2 will be included in our study and will be matched based on their age and gender with patients admitted with similar symptoms who will be tested negative for SARS-COV-2. The electronic medical charts of the study subjects will be reviewed and relevant demographic, clinical, laboratory and imaging findings will be de-identified and recorded. Demographic characteristics including age at the time of diagnosis, gender, race and BMI will be collected. Past medical history including CAD, heart failure with reduced or preserved ejection fraction, AF, hypertension, dyslipidemia, DM, smoking status as well as home medication will be abstructed. The name and daily dose of ACE inhibitors or ARB will be recorded. Laboratory values including cardiac enzymes, electrolytes, Haemoglobin and creatinine will be collected. Available EKG and TTEs will be individually reviewed by an independent cardiovascular disease fellow or faculty member. Finally clinical outcomes including need for mechanical ventilation, length of intensive care unit stay, length of hospitalization, arrhythmias, cardiac arrest and in hospital mortality will be abstructed from the electronic charts.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 80.00 Year(s)(—)
性别
All

入选标准

  • Age more than 18 years
  • Laboratory confirmed COVID-19 patients
  • SpO2 less than 94%
  • Patients on different modalities of oxygen therapy
  • Patients with radiologically confirmed pneumonia
  • ARDS or Acute Respiratory Failure Control
  • COVID-19 RTPCR negative 3.

排除标准

  • Moribund patient with septicemia with or without multiorgan dysfunction
  • Patient unwilling to participate in the study.

结局指标

主要结局

1. Need for mechanical ventilation

时间窗: Within 28 days from CCU admission

3. Length of hospitalization

时间窗: Within 28 days from CCU admission

2. Length of CCU stay

时间窗: Within 28 days from CCU admission

4. Incidence of arrhythmia, cardiac arrest during CCU stay

时间窗: Within 28 days from CCU admission

5. Final outcome-discharge or death

时间窗: Within 28 days from CCU admission

次要结局

  • All cause mortality(Within 28 days from CCU admission)

研究者

发起方
Dr Swati Datta
申办方类型
Other [individual]

研究点 (1)

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