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临床试验/NCT06842407
NCT06842407招募中不适用

Nuovi Bersagli Per lo Sviluppo di Anticorpi Monoclonali Per Immunoterapia - (Novel Targets for the Development of Monoclonal Antibodies for Immunotherapy)

Checkmab S.r.l.1 个研究点 分布在 1 个国家目标入组 600 人开始时间: 2023年4月1日最近更新:

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
600
试验地点
1
主要终点
Validation of molecular targets for immunotherapy

研究概览

简要总结

The first objective of the project consists in the preclinical validation of new possible molecular targets associated with intratumoral T regulatory cells. The second objective consists in the selection of monoclonal antibodies with therapeutic potential, specific for the selected targets.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • blood donors
  • age of 18 years or more
  • able to sign informed consent

排除标准

  • age below 18 years
  • Positive for HIV, HCV, HBV
  • not suitable for blood donation
  • not able to understand or sign informed consent

结局指标

主要结局

Validation of molecular targets for immunotherapy

时间窗: 04.2023-06.2026

Selection of therapeutic antibodies

时间窗: 04.2023-06.2026

次要结局

  • Set up of immunological assays to adress monoclonal antibodies mechanism of action(04.2023-06.2026)

研究者

发起方
Checkmab S.r.l.
申办方类型
Industry
责任方
Sponsor

研究点 (1)

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