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临床试验/NCT07601503
NCT07601503尚未招募不适用

In-line Chlorination for Drinking Water Treatment in Nigeria

University of California, Berkeley2 个研究点 分布在 1 个国家目标入组 2,655 人开始时间: 2026年5月26日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
2,655
试验地点
2

研究概览

简要总结

This study evaluates the implementation and effectiveness of in-line chlorination (ILC) for improving drinking water quality in rural Nigeria. Unsafe drinking water remains a major contributor to diarrheal disease, particularly among children under five. Inline chlorination is a passive water treatment approach that automatically doses chlorine at community water systems without requiring electricity or daily user action. Two cluster randomized controlled trials will be conducted in Kano State (North-West Nigeria) and Cross River State (South-South Nigeria). Communities will be randomized to either receive in-line chlorination installed at eligible communal water systems or serve as controls with no chlorination. The unit of randomization is a community or a cluster of communities that share water system for drinking water. The primary objective is to estimate the causal impact of in-line chlorination on household drinking water quality. Outcomes include the prevalence of Escherichia coli contamination in tap water and stored household water as well as the presence of free chlorine residual. Secondary objectives assess water source usage and adoption of chlorinated sources, as well as reduction in diarrheal disease. Implementation fidelity and operational performance of chlorination devices will also be monitored.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
None

入排标准

年龄范围
15 Years 至 —(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adult (18+) or emancipated minor (15+) pregnant women and women with children under 5 years old who do not plan to permanently move in the next 12 months.
  • Must be knowledgeable about the household's water collection and management practices

排除标准

  • Non-age-eligible women. Men and non-emancipated minors. Women who do not consent.

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Amy Janel Pickering

Associate Professor

University of California, Berkeley

研究点 (2)

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