NCT06427044尚未招募不适用
Effect of Bupivacaine Liposome Anterior Serratus Deep Block on Chronic Pain After Breast Cancer Surgery: a Randomized Controlled Study
Lu Hua1 个研究点 分布在 1 个国家目标入组 143 人开始时间: 2024年5月25日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 143
- 试验地点
- 1
- 主要终点
- Incidence of chronic pain 3 months after surgery
研究概览
简要总结
This study aims to investigate the effect and influence of liposome bupivacaine anterior serrat plane block on postoperative chronic pain in breast cancer patients, evaluate the therapeutic effect of liposome bupivacaine in postoperative chronic pain, and provide a new method for patients with postoperative chronic pain.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Adult patients (aged ≥18 years) who are scheduled to undergo unilateral modified radical breast cancer surgery
排除标准
- •Patients with coagulation dysfunction
- •There are infected patients at the puncture site
- •For patients allergic to any trial drug
- •Patients who take painkillers within 48 hours before surgery
- •Severe cardiopulmonary insufficiency, such as EF< 40%, FEVC < 50% expected; Uncontrolled hypertension;
- •Refuse to perform nerve block puncture
- •Mental disorders, epilepsy history;
- •Unable to give informed consent or are participating in other clinical trials.
研究组 & 干预措施
Anterior serratus block group
Experimental
Bupivacaine lipid 20mL (20mL 266mg bupivacaine liposomes) was ultrasound-guided for a single anterior serranus plane block
干预措施: Anterior serratus block group (Drug)
结局指标
主要结局
Incidence of chronic pain 3 months after surgery
时间窗: Three months after surgery
Pain levels were measured three months after surgery
次要结局
未报告次要终点
研究者
Lu Hua
Assistant Professor
Tongji Hospital
研究点 (1)
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