NL-OMON52079尚未招募4 期
The effect of extra hydration on kidney function during carboplatin-pemetrexed-pembrolizumab in patients with advanced non-small cell lung cancer.;*Hydration to prevent nephrotoxicity due to pemetrexed (HydraPem Study)* - HydraPem Study
适应症
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 入组人数
- 118
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 64（—）
入选标准
- •Age > 18 years
- •Patients must be willing and capable of giving written informed consent
- •Patients with advanced non-squamous cell lung cancer, receiving first line
- •treatment with pemetrexed/pembrolizumab maintenance after
- •carboplatin/pemetrexed/pembrolizumab.
- •Adequate hematological, renal and liver functions.
排除标准
- •Subject with an active auto-immune disease requiring systemic treatment
- •Lung disease requiring systemic steroids in doses of >10 mg prednisolone (or
- •equivalent dose of another steroid)
- •Previous allogeneic or organ transplant
- •Known heart failure
- •Myocardial infarction previous 6 months
- •Serious concomitant systemic disorders (for example active infection,
- •unstable cardiovascular disease) which in the opinion of the investigator would
- •compromise the patient's ability to complete the study, or would interfere with
- •the evaluation of the efficacy and safety of the study treatment
研究者
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