Oral D Mannose in the Prevention and Treatment of Recurrent Urinary Tract Infections: a Systematic Review
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- research literature data on d mannose for prevention and treatment of recurrent urinary tract infections.
研究概览
简要总结
The aim of this review is to address clinical reliability, efficacy and safety of long-term treatment with oral D Mannose for the prevention of recurrent urinary tract infections (RUTIs) in females.
详细描述
A comprehensive systematic MEDLINE, Embase, Cochrane search was performed for English language reports published before December 2018 using the term "recurrent urinary tract infections and d mannose." We searched Medline, Embase, and the Cochrane Register of Controlled Trials since January 2010 to December 2018. Eligible studies did not include non-oral therapy, local (vaginal) treatment in women with RUTIs.
Study eligibility criteria- We identified eligible original articles. The heterogeneity of the available studies, their different rationale and aim, the assumption of d mannose for prophylaxis or treatment of recurrent UTIs need to be taken into account.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •recurrent urinary tract infections (RUTIs)
排除标准
- •Upper urinary tract infections, severe clinical symptoms, fever > 37,5 with lumbar pain
结局指标
主要结局
research literature data on d mannose for prevention and treatment of recurrent urinary tract infections.
时间窗: January 2010-December 2018
literature search of the Medline, Embase, and Cochrane Library databases
次要结局
未报告次要终点
研究者
Daniele Porru
MD
Fondazione IRCCS Policlinico San Matteo di Pavia