跳至主要内容
临床试验/NCT06624540
NCT06624540招募中不适用

Effect of Implementing Evidence-based Practice and Nurse's Behavior Change on Quality of Care in Intensive Care Unit: Focus on Ventilator Associated Pneumonia in a Tertiary Hospital in Bangladesh

Hiroshima University3 个研究点 分布在 2 个国家目标入组 272 人开始时间: 2024年10月10日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
272
试验地点
3
主要终点
The nurse's skill performance is related to VAP checklist

研究概览

简要总结

Quality of care is crucial for preventing adverse events such as infection in the intensive care units (ICUs). The most common ICU-acquired infections include pneumonia such as ventilator-associated pneumonia (VAP), Central Line Bloodstream Infection (CLABSI), catheter-associated urinary tract in, Medical Device Related Pressure Ulcer (MDRPU) and Pressure Ulcer (PU). This study explores the patient outcome in ICU by examining the causes and prevalence of ICU-acquired infection. The implementation of evidence-based practice (EBP) to reduce infection and change the nurses practice (behavioral changes) to adhere with EBP based on simulation-based training.

General objective:

To evaluate the effect of EBP by using recent technologies-based equipment to prevent VAP and promote behavior change among nurses for better outcome of the patient in ICU.

Specific Objectives:

  1. To determine the incidence of adverse events (VAP rate, MDRPU rate, PU rate, CLABSI rate), length of stay and survival rate in ICU.
  2. To evaluate the effectiveness of EBP education by changing nurses' behavior and determine its impact on improving patient outcomes in the ICU.
  3. To evaluate the effectiveness of EBP including proper equipment use and changed nurses behavior acquired through the training for better patient outcome (VAP ratio) in the ICU.
  4. To examine the feasibility of evaluation process and outcomes and successful implementation of EBP in ICU.

Hypothesis:

It is hypothesize that implementing EBP in ICU, including new equipment use and nurses training, will improve patient outcome.

These research consist of three studies:

Phase 1: Incidence of adverse events (VAP rate, MDRPU rate, PU rate, CLABSI rate), length of stay and survival rate in ICU. The patients of General ICU will be followed up after admission up to discharge or death at ICU. The investigators use the study findings for our subsequent intervention study 3 as historical data.

Phase 2: A pre- and post- quasi-experimental study will be conducted for 6 months to evaluate the nurse's competency on EBP after getting 1-month EBP training. This study has 3 steps: (1) Pre-observation period to measure nurse's competency level for 2-month, (2) nurse's EBP training period with preparation for 1 month, and (3) post-implementation period to measure nurse's competency and implementation of EBP practice for 2 months. Study nurses will receive EBP training, EBP and proper equipment for patient management. The nurses will receive EBP education and training with necessary equipment, such as a close suction catheter, an endotracheal tube, a suction device, and a mouth care brush. In this study, use global standard equipment for the patients safety.

Phase 3: A pre- and post- quasi-experimental study will be implemented to evaluate the efficacy of EBP implementation. The investigators use new equipment and implement EBP for patients and assess the patient outcomes. The investigators compare the findings from study 1 (as historical data) with the data from this study 3.

The investigators will compare the VAP infection prevalence and patients' outcomes related to ICU-acquired infection between pre- and post- test phase.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Health Services Research
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Irrespective of age and sex, participant must be 18 years old.
  • Legal guardian of a patient consents to participation in the study
  • Intubated patients after admission.

排除标准

  • Who stays less than 2 days at the GICU.
  • Who dies or is extubated within 2 days after admitted in the GICU.
  • ICU readmission.

结局指标

主要结局

The nurse's skill performance is related to VAP checklist

时间窗: Study 2: 6 months

Nurses' skill performance related to VAP prevention measured using a researcher-developed 64-item observational checklist based on evidence-based practice guidelines. Unit of Measure: Total skill performance score (range 0-140), categorized as: * High: ≥112 (≥80%) * Moderate: 70-111 (50-79%) * Low: \<70 (\<50%)

Incidence rate of ventilator-associated pneumonia (VAP)

时间窗: 2 months

Number of new ventilator-associated pneumonia cases occurring in ICU patients during the study period. Unit of Measure: VAP cases per 1,000 ventilator days. Data will be collected: Patients' demographic data (age, sex, occupation etc.) Medical past and current history (diagnosis, treatment, medication, hospitalization). Reasons and date to be admitted to ICU. Treatment in ICU. Daily laboratory data taken in ICU. Daily biological data including vital signs. Results of patients' stay during ICU. Duration of ventilation Diagnosis of VAP

The nurse's skill performance is related to VAP checklist

时间窗: Study 2: 6 months

Nurses' skill performance related to VAP prevention measured using a researcher-developed 64-item observational checklist based on evidence-based practice guidelines. Unit of Measure: Total skill performance score (range 0-140), categorized as: * High: ≥112 (≥80%) * Moderate: 70-111 (50-79%) * Low: \<70 (\<50%)

Incidence rate of ventilator-associated pneumonia (VAP)

时间窗: 2 months

Number of new ventilator-associated pneumonia cases occurring in ICU patients during the study period. Unit of Measure: VAP cases per 1,000 ventilator days. Data will be collected: Patients' demographic data (age, sex, occupation etc.) Medical past and current history (diagnosis, treatment, medication, hospitalization). Reasons and date to be admitted to ICU. Treatment in ICU. Daily laboratory data taken in ICU. Daily biological data including vital signs. Results of patients' stay during ICU. Duration of ventilation Diagnosis of VAP

次要结局

  • A nurse's motivation level will be measured(6 month)
  • Nurses' sustained implementation measured(6 months)
  • Organizational readiness measured(6 months)
  • Nurses knowledge and practice related to VAP prevention measured.(6 months)
  • VAP episode(2 months)
  • Interval of VAP occurrence(2 months)
  • Micro-organism link to VAP(2 months)
  • Mortality and morbidity rate(2 months)
  • Onset of VAP(2 months)
  • Length of stay ICU patients(2 months)
  • Survival rate in ICU(2 months)
  • A nurse's motivation level will be measured(6 month)
  • Nurses' sustained implementation measured(6 months)
  • VAP episode(2 months)
  • Interval of VAP occurrence(2 months)
  • Organizational readiness measured(6 months)
  • Nurses knowledge and practice related to VAP prevention measured.(6 months)
  • Micro-organism link to VAP(2 months)
  • Mortality and morbidity rate(2 months)
  • Onset of VAP(2 months)
  • Length of stay ICU patients(2 months)
  • Survival rate in ICU(2 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Nahida Akhter

Principal Investigator, Ph.D Fellow, Graduate School of Biomedical and Health Sciences, Hiroshima University, Japan.

Hiroshima University

研究点 (3)

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