NCT06770049招募中不适用
Phenotype-Tailored Lifestyle Intervention for Obesity: A Randomized Trial
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- Mayo Clinic
- 入组人数
- 228
- 试验地点
- 2
- 主要终点
- Total Body Weight Loss (TBWL)
研究概览
简要总结
The purpose of this study is to develop an evidence-based precision medicine approach for obesity that enhances weight loss and promotes weight loss maintenance.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •men or women between 18 to 65 years with obesity (BMI>30kg/m2).
排除标准
- •weight change greater than 3% in the previous 3 months
- •history of bariatric surgery and bariatric endoscopy
- •untreated psychiatric disorders including binge eating disorders and bulimia
- •current use of AOMs
- •history of use of medications affecting weight or energy intake or energy expenditure in the last 6 months
- •history of type 1 diabetes mellitus or uncontrolled medical conditions (e.g., uncontrolled hypertension)
- •women who are pregnant or plan to become pregnant,
- •any condition that limits their participation in the study
- •Principal Investigator discretion
研究组 & 干预措施
Phenotype-tailored Lifestyle Intervention (PLI) program
Experimental
干预措施: Phenotype-tailored Lifestyle Intervention (PLI) program (Behavioral)
Standard Lifestyle Intervention (SLI) program
Active Comparator
干预措施: Standard Lifestyle Intervention (SLI) program (Behavioral)
结局指标
主要结局
Total Body Weight Loss (TBWL)
时间窗: Baseline, 52 weeks
Change in Total Body Weight Loss (TBWL) in kg
次要结局
未报告次要终点
研究者
Andres J. Acosta, M.D., Ph.D.
Principal Investigator
Mayo Clinic
研究点 (2)
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