The Role of Incorporating Acacia Gum in Foods on Glucose Homeostasis in Healthy Humans: a Pilot Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 14
- 试验地点
- 1
- 主要终点
- postprandial blood glucose
研究概览
简要总结
Abnormal postprandial blood glucose (PPG) is considered as a strong predictor for developing metabolic diseases worldwide. Nowadays, little understanding is available on how a carbohydrate-rich food matrix and the starch structures within interact with the gastrointestinal tract to help in controlling PPG. In this investigation, the use Acacia gum enriched flour will be used to explore the effect of adding the gum as food supplement on PPG in healthy humans.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Male and female self-reported healthy volunteers (aged 18 to 40 years)
- •Normal to overweight individuals (body mass index (BMI) 18.5-30 kg/m2) o BMI is equal to body weight (kg) divided by height squared (m2)
排除标准
- •History of substance abuse
- •Excessive alcohol intake
- •Pregnancy
- •Cardiovascular disease
- •Any gastrointestinal disease e.g. irritable bowel syndrome or inflammatory bowel disease
- •Kidney disease
- •Liver disease
- •Pancreatitis
- •Use of medications likely to interfere with energy metabolism, appetite regulation and hormonal balance, including: anti-inflammatory drugs or steroids, antibiotics, androgens, phenytoin, erythromycin or thyroid hormones.
研究组 & 干预措施
Acacia gum incorporated biscuits
Acacia gum incorporated biscuits
干预措施: incorporating acacia gum flour into commonly consume foods (Dietary Supplement)
control biscuits
control biscuits
结局指标
主要结局
postprandial blood glucose
时间窗: 0 minutes and postprandial timepoints: 15 minutes, 30 minutes, 60 minutes,120 minutes,180 minutes
次要结局
未报告次要终点
研究者
Mai Khatib
Dr.
King Abdulaziz University