Pilot Study to Test the Effect of Fractionalized Vigorous-Intensity Activity on Acute Glucose in Adults at Risk for Type 2 Diabetes
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- Continuous Glucose Monitor
研究概览
简要总结
This pilot study seeks to demonstrate feasibility to conduct data collection and illustrate potential for effect of fractionalized bouts of stair climbing on glucose control in adults at risk for type 2 diabetes.
详细描述
Objective
Compare the short-term effects of two different fractionalized stair climbing bout protocols on glucose control among adults at risk for type 2 diabetes.
Rationale: Fractionalized physical activity is associated with reduced BMI, glycated hemoglobin, lower 2-hr plasma glucose and insulin sensitivity in cross-sectional studies. Yet, few studies have examined the effects of fractionalized or intermittent physical activity in a prospective manner. Furthermore, the research is limited to patients with diagnosed type 2 diabetes, or using exercise of a moderate intensity.
The hypothesis is that stair climbing, a vigorous-intensity activity, may have a greater health effect. However, this has not been tested in short bouts of activity that are spread out during a day.
Implications: Fractionalized physical activity may be more feasible for adults at risk for, or with diagnosed type 2 diabetes who are not currently active. These short bouts can increase energy expenditure throughout the day, rather than in one long continuous bout as currently recommended.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 40 Years 至 64 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age greater than 40 years but less than 65 years (working age adult with reduce physiologic capacity to regulate glucose)
- •BMI of overweight or obese (25.0 to 35.0)
- •Answered "No" to all questions on the Physical Activity Readiness Questionnaire, or has physician approval to participate
- •Hemoglobin A1C% value in the at-risk range of 5.7 to 6.4
排除标准
- •Unable to physically perform stair climbing
- •Currently exercising for 60 or more minutes weekly.
- •Weight over 275 lbs (because stair climbing machine has a weight limit)
研究组 & 干预措施
Stair Climbing 4x/day
Participants use the stair climber 4 times per day, for 4 minutes at a time. Total dose = 16 minutes.
干预措施: Stair Climbing Frequency (Behavioral)
Stair Climbing 8x/day
Participants use the stair climber 8 times per day, for 2 minutes at a time. Total dose = 16 minutes.
干预措施: Stair Climbing Frequency (Behavioral)
结局指标
主要结局
Continuous Glucose Monitor
时间窗: Up to 5 days
Participant has device inserted prior to dinner the night before the sedentary day, completes the sedentary day and two stair climbing days, then has the device removed on the morning of the 5th day.
次要结局
- Heart Rate(2 Intervention Days)
研究者
Jennifer Gay
Assistant Professor
University of Georgia