Health Behavior Management Program for Patients With Coronary Heart Disease: A Clinical Study
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- 6MWD
研究概览
简要总结
Coronary artery disease (CAD) is a major chronic condition severely impacting population health in China. Our previous cohort studies revealed a high comorbidity rate between CAD and frailty, suggesting their interrelated equivalence as clinical syndromes with shared risk factors. In recent years, pilot integrated health management initiatives in China have demonstrated promising outcomes, yet evidence remains scarce regarding patients with concurrent CAD and frailty-a critical gap needing urgent resolution to achieve the "Healthy China 2030" strategic goals.
Building on prior research, this project aims to systematically evaluate existing management models for patients with CAD and frailty, develop a tailored health management framework, and implement it in clinical settings through empirical studies. The model will be optimized according to regional and demographic variations, leveraging cardiac rehabilitation centers, exercise-based interventions, and internet-enabled technologies to enhance coordinated care. By improving exercise efficacy, mitigating frailty progression, and enhancing quality of life, this initiative seeks to establish a robust chronic disease management system. The findings will provide evidence for formulating regional health policy and insurance strategies in Anhui Province, ultimately improving standardized management rates for chronic diseases.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 80 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of Coronary heart disease;
- •Proficiency in smartphone use;
- •Absence of visual, auditory, cognitive, or motor impairments.
排除标准
- •Inability or unwillingness to provide informed consent;
- •Physical or cognitive limitations preventing app operation;
- •Inability to attend in-person follow-up visits;
- •Concurrent severe comorbidities or malignancies, such as severe valvular heart disease, New York Heart Association class IV heart failure, severe aortic regurgitation, cancer, end-stage renal or liver disease;
- •Any other condition that could potentially impede exercise participation.
结局指标
主要结局
6MWD
时间窗: 1month,3 months, 6 months
Measuring the maximum distance within 6 minutes.
The MOS item short from health survey
时间窗: 1month,3 months, 6 months
Quality of life was assessed using the 36-Item Short Form Health Survey questionnaire
次要结局
- Physical activity level(1month,3 months, 6 months)
- Systolic pressure/Diastolic pressure(1month,3 months, 6 months)
- Frailty(1month,3 months, 6 months)
- Grip strength(1month,3 months, 6 months)
- Gait speed(1month,3 months, 6 months)
- Major cardiovascular adverse events(1month,3 months, 6 months)
- Changes in Blood Lipid Biomarkers(1 month, 3 months, 6 months)
研究者
Zhou,Tong
Associate Professor
The First Affiliated Hospital of Bengbu Medical University
