Comparative study of efficacy and safety profile of topical Metronidazole and topical Tacrolimus in Steroid induced Rosacea in tertiary care teaching hospital Haldwani
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- 1.To compare the efficacy of 0.75% metronidazole gel and 0.03% tacrolimus cream in steroid induced rosacea.
研究概览
简要总结
Rosacea is a chronic, inflammatory skin disease of obscure etiology,characterizd by facial erythema and telangiectasia with varying degree of inflammatory skin lesion like papule and pustule. The disease is though to be of immune origin. main precipitating event proposed for the disease include UV light, microbes and hormonal imbalance.
As there is scarcity of data regarding use and effectiveness of topical metronidazole and tacrolimus cream in steroid induced rosacea in patients of kumaon region, so this study will be done in department of Dermatology and Department of Pharmacology of GMC Haldwani.
研究设计
- 研究类型
- Interventional
- 分配方式
- Random Number Table
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Patients of either sex with steroid induced rosacea.
- •2.Age 18 years and above.
排除标准
- •1.Pregnant and Lactating Women.
- •2.Drug allergy .
- •Children less than 18 years 4.Patients with systemic disease.
结局指标
主要结局
1.To compare the efficacy of 0.75% metronidazole gel and 0.03% tacrolimus cream in steroid induced rosacea.
时间窗: The patients will be followed up on 1st, 3rd, 5th and 8th week
次要结局
- 1. To Study the adverse effects of 0.75% metronidazole gel and 0.03% tacrolimus cream.(2. To study the cost of the therapy.)