EUCTR2004-001108-11-DE进行中（未招募）1 期
A phase II study of intravenous TZT-1027, administered weekly times two, every three weeks, to patients with advanced or metastatic soft tissue sarcomas (STS) with prior exposure to doxorubicin-based chemotherapy
European Organisation for the Research and Treatment of Cancer0 个研究点目标入组 28 人开始时间: 2004年9月23日最近更新:
适应症
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 28
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •? Histological evidence of high or intermediate grade malignant progressive or metastatic soft tissue sarcoma
- •? The following tumor types are eligible (WHO classification, 2002, see appendix G)
- •? Adipocytic (liposarcoma dedifferentiated, myxoid/round cell, pleomorphic, mixed-type,NOS)
- •? Fibroblastic (adult fibrosarcoma, myxofibrosarcoma, sclerosing epithelioid fibrosarcoma)
- •? So-called fibrohistiocytic (pleomorphic MFH”, giant cell MFH”, inflammatory MFH”)
- •? Leiomyosarcoma (non-organ origin, uterine origin or skin origin)
- •? Skeletal muscles (rhabdomyosarcoma, alveolar or pleomorphic) excluding embryonal rhabdomyosarcoma
- •? Vascular (epithelioid haemangioendothelioma, angiosarcoma)
- •? Uncertain differentiation (synovial, epithelioid, alveolar soft part, clear cell, desmoplastic
- •small round cell, extra-renal rhabdoid, malignant mesenchymoma, PEComa, intimal
- •sarcoma) excluding chondrosarcoma, Ewing tumors / PNET
- •? Malignant peripheral nerve sheath tumors
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •? The following tumor types are ineligible
- •? Malignant glomus tumors
- •? Embryonal rhabdomyosarcoma
- •? Chondrosarcoma
- •? Osteosarcoma
- •? Ewing tumors / PNET
- •? Gastro-intestinal stromal tumors
- •? Malignant solitary fibrous tumors
- •? Dermofibromatosis sarcoma protuberans
- •? Inflammatory myofibroblastic sarcoma
- •? Neuroblastoma
- •? Malignant mesothelioma
- •? Mixed mesodermal tumors of the uterus
- •? Other tumors of organ origin, except uterine and skin leiomyosarcoma
研究者
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